نتایج جستجو برای: absolute risk reduction
تعداد نتایج: 1459675 فیلتر نتایج به سال:
In this issue Simes et al. present pooled estimates for mortality from the Pravastatin Pooling Project (PPP). The two secondary prevention studies and the primary prevention trial included in the PPP enrolled together about 20 000 men and women aged 45–75 years with or without established coronary artery disease and a wide range of baseline lipid levels. As compared to placebo, in those allocat...
The relative reduction of risk for all-cause mortality among the elderly has been described as attenuated compared to younger subjects, but the risk for all-cause mortality increases with age when absolute risk is considered. The objectives of the present inquiry were to calculate the relative and absolute risks of all-cause mortality based on incidence rate ratios, and summarize these risks fo...
AIMS We evaluated the relationship of renal function and ischaemic and bleeding risk as well as the efficacy and safety of ticagrelor in stable patients with prior myocardial infarction (MI). METHODS AND RESULTS Patients with a history of MI 1-3 years prior from PEGASUS-TIMI 54 were stratified based on estimated glomerular filtration rate (eGFR), with <60 mL/min/1.73 m(2) pre-specified for an...
BACKGROUND The medical profession is often presented with information on the value of treatment in terms of likely risk reduction. If this same information was presented to patients--so enabling them to give proper informed consent--would this affect their decision to be treated? AIM To examine patients' choice about treatment in response to different forms of risk presentation. DESIGN OF S...
OBJECTIVE To examine the relationship between hospital volume and mortality for nonsurgical patients receiving mechanical ventilation. DATA SOURCES Pennsylvania state discharge records from July 1, 2004, to June 30, 2006, linked to the Pennsylvania Department of Health death records and the 2000 United States Census. STUDY DESIGN We categorized all general acute care hospitals in Pennsylvan...
OBJECTIVE To determine whether some participants in the Diabetes Prevention Program were more or less likely to benefit from metformin or a structured lifestyle modification program. DESIGN Post hoc analysis of the Diabetes Prevention Program, a randomized controlled trial. SETTING Ambulatory care patients. PARTICIPANTS 3060 people without diabetes but with evidence of impaired glucose me...
BACKGROUND Coronary heart disease (CHD) is the leading cause of death in the United States. Previous research examining physicians ability to estimate cardiovascular risk has shown that physicians' generally overestimate the absolute risk of CHD events. This question has, however, only studied risk prediction for a limited number of patient care scenarios. The aim of this study is to measure th...
STUDY OBJECTIVE s: To assess the accuracy of physicians' judgments of survival probability for medically managed patients with coronary artery disease (CAD), and of the absolute risk reduction of mortality due to coronary artery bypass grafting (CABG) or percutaneous transluminal coronary angioplasty (PTCA) for such patients; and relationships among these judgments and the physicians' propensit...
BACKGROUND AND PURPOSE We assessed whether the effects of surgical decompression for space-occupying hemispheric infarction, observed at 1 year, are sustained at 3 years. METHODS Patients with space-occupying hemispheric infarction, who were enrolled in the Hemicraniectomy After Middle cerebral artery infarction with Life-threatening Edema Trial within 4 days after stroke onset, were followed...
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