OBJECTIVES To identify venous thromboembolism (VTE) disease-susceptibility genes. PATIENTS AND METHODS We performed in silico genome wide association scan (GWAS) analyses using genotype data imputed to approximately 2.5 million single-nucleotide polymorphisms (SNPs) from adults with objectively-diagnosed VTE (n=1503), and controls frequency matched on age and gender (n=1459; discovery populat...

In past and ongoing military conflicts, the use of whole blood (WB) as a resuscitative product to treat trauma-induced shock and coagulopathy has been widely accepted as an alternative when availability of a balanced component-based transfusion strategy is restricted or lacking. In previous military conflicts, ABO group O blood from donors with low titers of anti-A/B blood group antibodies was ...

We evaluated the distribution of ABO and Rhesus (Rh) D blood groups in the population of Poonch district in Azad Jammu and Kashmir. The blood group phenotypes were detected by the classic slide method. The ABO blood group system in the total sample showed the same trend of prevalence as for the general Indian subcontinent (B > or = O > A > AB). The same trend was found among males, but among fe...

Studies of the abnormal oocyte (abo) gene of Drosophila melanogaster have previously been limited to the analysis of a single mutant allele, abnormal oocyte1 (abo1). The abo1 mutation causes a maternal-effect lethality that can be partially rescued zygotically by the abo+ allele and by increasing the dosage of specific regions of heterochromatin denoted ABO. This report describes the properties...

INTRODUCTION A 4-year collaborative project between the American Board of Orthodontics (ABO) and 15 American orthodontic graduate programs concluded at the ABO Clinical Examination in February 2006. METHODS Fifty recent graduates (the pilot study group) presented cases that were treated in their graduate programs as partial fulfillment of the requirements for ABO certification. The examinees ...

OBJECTIVE The aim of this study was to elucidate clinical trial efficacy, safety, and dosing practices of abobotulinumtoxinA (ABO) treatment in adult patients with upper limb spasticity (ULS). METHODS A systematic literature review was performed to identify randomized controlled trials and other comparative clinical studies of ABO in the treatment of adult ULS published in English between Jan...

THE LIVER has long been regarded as a privileged organ which can be transplanted across incompatible ABO blood groups with little risk of hyperacute rejection. l However, in a recent review of 671 first, second, and third liver transplants we found a significant advantage for ABO donor-recipient identity for primary liver transplants.2 Although a large number of ABO mismatched grafts were succe...

ABO antigens are known to be oligosaccharide antigens, and are widely expressed on the membranes of red blood cells and tissue cells. Therefore, the determining ABO blood group antigens is important in both transfusion and organ transplantation, and is one of the markers used for personal identification in forensics. The ABO blood group is currently determined by the presence of A and B antigen...

Otkrićem ABO sustava krvnih grupa 1900. godine austrijski liječnik Karl Landsteiner utemeljio je transfuzijsko liječenje. Radom Yamamota 1990. klonirani su ABO geni, što je omogućilo naprednije strukturne i funkcionalne analize ABO sustava (1). Humani ABO gen smješten je na kromosomu 9 (9q34.1-q34.2). Sadrži 7 eksona i 6 introna koji obuhvaćaju 18 kb genomske DNA. Svaki tip krvne grupe sustava ...

BACKGROUND The aim was to elucidate clinical trial efficacy, safety, and dosing practices of abobotulinumtoxinA (ABO) treatment in adult patients with blepharospasm and hemifacial spasm. To date, most literature reviews for blepharospasm and hemifacial spasm have examined the effectiveness of all botulinum neurotoxin type A products as a class. However, differences in dosing units and recommend...