Immunochemical studies support the view that carcinoembryonic antigens from entodermally derived adenocarcinomata are incomplete blood group substances of the ABO system. The deficient antigens have a tumor-specific activity, due to unmasking of a structural sequence that is cryptic in the normal situation. Two other serological activities of the tumor antigens are determined by ./V-acetylgalac...

ABO-incompatible (ABO-i) living-donor liver transplantation (LDLT) is performed if an ABO-compatible graft cannot be obtained. However, a perfect desensitization protocol has not been established worldwide, especially for simultaneous ABO-i LDLT and splenectomy. We herein report two cases of ABO-i LDLT. To the best of our knowledge, this is the first case report of ABO-i LDLT in an adult patien...

-Patients with melanoma who had one or more close relatives with melanoma were studied for their natural-killer-cell (NK) activity against cultured melanoma cells and Chang cells. A high proportion of the patients and their relatives were found to have low NK activity against these target cells. In most of the patients this could not be attributed to general depression of their immune function,...

BACKGROUND & OBJECTIVES Indian population is characterized by the presence of various castes and tribal groups. Various genetic polymorphisms have been used to differentiate among these groups. Amongst these, the ABO blood group system has been extensively studied. There is no information on molecular genotyping of ABO blood groups from India. Therefore, the main objective of this study was to ...

By JOSEPH H. LAPIN, ANDREW HORONIcK AND ROBERT H. LAPIN T HE COMPLETE SEPARATION of viable leumkocytes from the erythrocytes of peripheral human blood, in a manner satisfactory for immunologic procedures, has never been achieved. As a consequence, all of the work on agglutination phenomena and the demonstration of ABO group antigens in leukocytesl*3 becomes subject to criticism. Riis4 described...

BACKGROUND/AIMS We investigated the impact of the baseline anti-A/B antibody titer on the clinical outcome in ABO-incompatible kidney transplantation (IKT). METHODS We included 183 patients who had undergone KT (40 ABO IKT and 143 ABO-compatible KT). Eight patients with a baseline titer of ≥1:512 were assigned to the high-titer group and 32 patients with a baseline titer of ≤1:256 were assign...

It is widely accepted that the serum of healthy individuals contains natural antibodies only against those blood group A or B antigens that are not expressed on the individual's red blood cells. The mechanisms involved in tolerance to autologous blood group antigens remain unclear. In the present study, we show that IgM and IgG antibodies reactive with autologous blood group antigens are presen...

Depending on the ABO blood group, gonorrhea may affect the titers of isohemagglutinins compared with those of uninfected controls. The isohemagglutinin titers in group O patients were significantly increased (P less than 0.001) against erythrocytes A, B, and AB. In group A patients, only the titer against AB erythrocytes was significantly increased. In group B patients, the titer against AB ery...

BACKGROUND & OBJECTIVES Literature reports several studies on ABO groups and malaria but a study with an adequate sample size and controls is not available. ABO groups are genetically controlled, hence, large sample size and comparison with population frequency is essential. To determine whether malaria infection with variable severity has correlation with ABO groups. STUDY DESIGN & METHODS B...

The Antimicrobial proteins(AMPs) of kidney, liver, heart and gills of Labeo rohita were partially purified by acid extraction and ammonium sulphate precipitation. The proteins extracted from the tissues were estimated and found to be 106.5 mg, 64.0 mg, 160.0 mg and 48.2 mg/g.wet.wt respectively. Out of the four organs, the heart tissue has yielded the highest amount of protein i,e 160 mg /g wet...