Development of the central nervous system is controlled by both intrinsic and extrinsic signals that guide neuronal migration to form laminae. Although defects in neuronal mobility have been well documented as a mechanism for abnormal laminar formation, the role of radial glia, which provide the environmental cues, in modulating neuronal migration is less clear. We provide evidence that loss of...

The pathological effect of multiple sclerosis in the visual pathways consists of axonal demyelination and axonal loss. These two consequences of the disease, even in its subclinical stages, are reflected in changes in the initial component of the visual evoked response (VER) affecting its latency, configuration, or both. These abnormal early components of the VER were recorded in 25 patients wi...

The use of network appliances, i.e., computer systems specialized to perform a single function, is becoming increasingly widespread. Network appliances have many advantages over traditional general-purpose systems such as higher performance/cost metrics, easier configuration and lower costs of management. Unfortunately, while the complexity of configuration and management of network appliances ...

typically, two configurations are used for energy harvesting, with different advantages: piezoelastic and piezomagnetoelastic. best performance of piezoelastic configuration is limited to its narrow bandwidth around the resonance frequency. if the excitation frequency slightly deviates from the resonance frequency, the power-out is severely reduced. to overcome this, the piezomagnetoelastic has...

It is well-established that there are trillions of gut microbiota (GM) in the human gut. GM and its metabolites can reportedly cause cancer by causing abnormal immune responses. With development sequencing technology application germ-free models recent years, significant inroads have been achieved research on microbiota-related metabolites. Accordingly, role mechanism colorectal (CRC) gradually...

Automated control weaknesses are associated with defects in computer hardware or computer applications. AU 319 does not require auditors to add professionals with specialized skills in automated controls (or IT audit specialists) to the audit engagement. Auditors may encounter a material automated control weakness and adjust their audit plan without the assistance of an IT audit specialists. Th...

Cleaning pipeline networks is a routine operation in almost every chemical plant. Our aim is to develop a systematic strategy to generate the needed operating procedures with Petri-net models. Specifically, the proper materialtransfer routes are selected on the basis of the Petri-net representation of all possible paths. The equipment models are then attached to this path model according to net...

Nowadays, companies have to report a large number of data sets (e.g., sustainability data) regarding their products to different legal authorities. However, in today’s complex supply chains products are the outcome of the collaboration of many companies. To gather the needed data sets, companies have to employ cross-organizational and long-running data collection processes that imply great vari...