Background and Purpose: Candidiasis, an important fungal infection, is considered the fourth most common nosocomial blood stream infection. Nowadays, because of increased fungal resistance to antibiotics, the use of herbal medicine has gained particular attention. Cyclamen species are medicinal plants containing triterpenoid saponins, which are shown to have antimicrobial properties. Materi...

Over the last 30 years, the growing immunocompromised population has created fertile ground for opportunistic pathogens, particularly those from the Kingdom Fungi. While the range of fungal species causing infections is increasing, there remain three key culprits [1]. Firstly, the ascomycete yeast Candida albicans is responsible for the greatest number of fungal infections, particularly those a...

BACKGROUND AND OBJECTIVE: Candida albicans infection is a problem of growing clinical importance, particularly in immunocompromised populations. This study aimed to investigate the inhibitory effect of carvacrol on the hyphae formation and expression of C. albicans HWP1. METHODS: This cross-sectional study was done over a 6-month period in 2016-2017. Vaginal, mouth and  skin surface swabs were...

The frequency of severe systemic fungal diseases has increased in the last few decades. The clinical use of antibacterial drugs, immunosuppressive agents after organ transplantation, cancer chemotherapy, and advances in surgery are associated with increasing risk of fungal infections. Opportunistic pathogens from the genera Candida and Aspergillus as well as pathogenic fungi from the genus Cryp...

AIMS To test the bactericidal activity of standard organ culture medium, and to compare the sensitivity and rapidity of blood culture bottles with conventional microbiological methods for detection of bacteria and fungi inoculated in a standard cornea organ culture medium. METHODS The bactericidal activity of contaminated standard organ culture medium containing 100 IU/ml penicillin, 0.1 mg/m...

Background & Aim: In recent years using from plant product has been considered wildly as main factor for preventing pathogenic diseases cassed by attacking viruses, bacteria, fungi and parasites. There are some funguses which could be the factors for affliction of some diseases in human, plants and animals. Plant extracts are those which could act and be used as preventing from these diseases a...

BACKGROUND Fungal infections affect various parts of the body and can be difficult to treat. Aspergillus infection causes a spectrum of diverse diseases particularly in lung according to host immunity. The two major entities are invasive pulmonary aspergillosis and chronic pulmonary aspergillosis. Candida infections can be superficial or invasive. Superficial infections often affect the skin or...

ABSTRACT: Candidiasis is a fungal infection caused by Candida albicans. Allium sativum (garlic) and Curcuma longa (turmeric) have been used as antifungal agents. The main aim of this study was to identify the effectiveness of these natural products towards C. albicans and on their pharmacological and toxicity aspects. Thus, agar disc diffusion method was used to study the antifungal activity of...

The study aimed to identify the HWP1 gene in non-Candida albicans Candida species and the differential expression of HWP1 following treatment with Piper betle and Brucea javanica aqueous extracts. All candidal suspensions were standardized to 1 × 10(6) cells/mL. The suspension was incubated overnight at 37 °C (C. parapsilosis, 35°C). Candidal cells were treated with each respective extract at 1...

Background and Purpose: Candida albicans is the most prevalent Candida species isolated from animals. Candidiasis can be systemic in animals or may affect a single organ, such as the mouth, urinary tract, and skin. The aim of the present study was to determine the genetic diversity of C. albicans isolated from different animals and investigate the presence of a relationship between host specifi...