Context Enterprise databases contain not only data but also queries: • view definitions • stored procedures • usage logs • workloads • software engineering Stored as long strings… ! Difficult to query in standard SQL

This thesis presents an automated, data-driven integration process for relational databases. Whereas previous integration methods assumed a large amount of user involvement as well as the availability of database meta-data, we make no use of meta-data and little end user input. This is done using a novel join and translation finding algorithm that searches for the proper key / foreign key relat...

Model-Driven Software Engineering (MDSE) aims to provide automated support for the development, maintenance and evolution of software by performing transformations on models. During these transformations model elements are traced from a more abstract model to a more concrete model and vice versa, achieved through meta-modeling. Software development process produces numerous models of complex ap...

Enterprise information systems (EIS) often employ relational database systems to store their content. At the same time, XML constitutes the dominant standard for data exchange as well as for the hypertext level of webenabled EIS. Thus, the integration of XML with relational database systems to allow the storage, retrieval, and update of XML documents is of paramount importance in the context of...

We outline a paradigm for meta-microarray database creation and integration with clinical variables. We use as our implementation example a breast cancer database linking RNA expression measurements (by microarray) and clinical variables, such as survival metrics and tumor size. Such an endeavor involves integrating across different microarray datasets as well as clinical parameters. To this en...

INTRODUCTION Self-monitoring of blood pressure (BP) is an increasingly common part of hypertension management. The objectives of this systematic review were to evaluate the systolic and diastolic BP reduction, and achievement of target BP, associated with self-monitoring. METHODS MEDLINE, Embase, Cochrane database of systematic reviews, database of abstracts of clinical effectiveness, the hea...

RESEARCH DESIGN AND METHODS Bibliographic databases were searched up to July 2012. Included studies had a follow-up of ‡12 months and outcomes comparing change in body composition, glycemic control, or progression to diabetes. Lifestyle interventions aimed to translate evidence from previous efficacy trials of diabetes prevention into realworld intervention programs. Data were combined using ra...

The Human Genome Project poses severe challenges in database design and implementation. These include comprehensive coverage of diverse data domains and user constituencies; robustness in the presence of incomplete, inconsistent and multi-version data; accessibility through many levels of abstraction, and scalability in content and organizational complexity. This paper presents a new dataion, a...

Practical experience shows that the design of very large database schemata causes severe problems, and no systematic support is provided. In this paper we address this problem. We define an Entity-Relationship schema algebra, which permits the representation of very large database schemata by algebraic expressions involving smaller schemata. Similar to abstraction mechanisms found in semantic d...