Please see the full text contains the Pesian abstracts for this volume.

the aryl-(z)-n-[2-amino-1,2-dicyanovinyl]formamidine 2 cyclize in solvent-free conditions and in the presence of a base to give a 5-amino-1-aryl-4-cyanoimidazoles 3. silica sulfuric acid as an efficient and reusable heterogeneous catalyst has been used for the preparation of amidines 2 from formimidate 1 through reaction with aromatic amines at room temperature and in good to excellent yields. ...

Selective functionalization reactions of aromatic and heteroaromatic halides with carbon, oxygen, and nitrogen nucleophiles have attracted much attention in the last decades. In addition to typical metal-catalyzed coupling reactions, direct functionalization of aryl halides through the formation of Grignard reagents offer new ways for the efficient construction of biologically interesting carbo...

Significance: A triptycene-based NHC-Pd mainchain organometallic microporous polymer (MOMP-1) was prepared from 2,6,14-triiodotriptycene according to Scheme 1. MOMP-1 catalyzed the Suzuki–Miyaura coupling of aryl halides with phenylboronic acid in water to give the corresponding biaryls in 88–97% yield (Scheme 2, 9 examples). Comment: The characterization of MOMP-1 was performed by NMR, SEM, TE...

To determine the relative contributions of tobacco smoking and P-450 metabolism (cytochrome P-450iAi) in the formation of benzo(a)pyrenediol-epoxide and other polycyclic aromatic hydrocarbon-DNA adducts in vivo, 16 human placentas were assayed for aryl hydrocarbon hydroxylase activity and (±)r-7,f-8-dihydroxy-c-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene-DNA adduci levels. Immunoaffinity chro...

Organocatalyst trityl chloride (Ph3CCl), by in situ formation of trityl carbocation with inherent instability, efficiently catalyzes the condensation of dimedone (5,5-dimethyl-1,3-cyclohexanedione) (2 equiv.) with arylaldehydes (1 equiv.) under solvent-free conditions to afford 9-aryl-1,8-dioxo-octahydroxanthenes in high to excellent yields and in relatively short reaction times. Formation of t...

The mechanism of esterification of the secondary alcohol 1-(1-naphthyl)ethanol 9 by isobutyric anhydride catalyzed by 4-pyrrolidinopyridine (PPY, 11) and a series of single enantiomer atropisomeric 4-dialkylaminopyridines 8a-g has been studied computationally at the B3LYP/6-311+G(d,p)//B3LYP/6-31G(d) level. Comparison of the levels of enantioselectivity predicted computationally with the result...

An efficient, novel bifunctional C2-symmetric ionic liquid–supported (S)-proline organocatalyst 7 was developed for a one-pot, five-component reaction involving ?-keto esters 8, aryl aldehydes 9, and amines 10, affording highly functionalized tetrahydropyridines 11a–o by simultaneous generation of fives bonds two stereogenic centers with extraordinary diastereo- enantioselectivities (up to >...

The reactivity of benzo[1,2-b:4,5-b']dithiophene-4,8-dione in Pd-catalyzed C-H arylation was investigated. Using aryl bromides as source the presence carbonate bases 1,4-dioxane mono-C2-arylated benzo[1,2-b:4,5-b']dithiophene-4,8-diones were regioselectively obtained. This procedure allowed to introduce both electron-rich and electron-poor substituents on unit. These conditions also effective f...