Large and small aggregates of Aβ peptides, resembling the morphology and dimensions of fibrillar and oligomeric forms of Aβ respectively, relevant to Alzheimer's disease, are stabilized on electrodes using self-assembly. Both of these forms were found to bind redox active Cu and heme, resulting in active sites having distinctive biophysical properties. The reduced metal bound Aβ active sites of...

Azo dye of quinoline named 5-(3-pyridylazo)-8-hydroxyquinoline (PAHQ) was prepared via coupling reaction diazonium salt 3-aminopyridine and 8-hydroxyquinoline. he PAHQ characterized by elemental analysis, mass spectroscopy 1H-NMR. The complexes were under 2:1 (L:M) mole ratio. infrared spectroscopy, UV-Vis, molar conductance, magnetic susceptibility. IR spectra data indicate that ligand is bid...

Acetylcholine activates nicotinic acetylcholine receptors (nAChRs) by binding to an extracellular site located at the interface of two adjacent subunits. In contrast, recent studies have provided evidence that positive allosteric modulators (PAMs) such as TQS (4-(naphthalen-2-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) and allosteric agonists such as 4BP-TQS (4-(4-bromophe...

Immobilization of poly[8-methacroyloxy-quinoline] on a natural saponite surface immediately after polymer formation has been performed. The adsorption properties the modified adsorbent with resp...

Quinoline is a typical nitrogenous heterocyclic compound, which carcinogenic, teratogenic, and mutagenic to organisms, its wastewater difficult biodegrade directly. The bipolar electro-Fenton process was employed treat quinoline solution. process/reaction conditions were optimized through the single factor experiment. degradation kinetics of chemical oxygen demand (COD) analyzed. To get mechani...

In the title compound, C(19)H(13)N(3)O, the dihedral angle between the two quinoline systems is 11.54 (3)°. The mol-ecular conformation is stabilized by intra-molecular N-H⋯N and C-H⋯O hydrogen bonds, with N-H⋯N being bifurcated towards the two N atoms of the two quinoline rings. In the crystal, there are weak intermolecular π-π inter-actions present involving the quinoline rings [centroid-cent...

New europium complexes of 3-oxo-1-hydroxy-quinoline-2-carboxylic acid amide derivatives (L1-L3), which are highly luminescent and do not require luminescence enhancers are reported. The luminescence intensity of the Eu-L1-3 complexes was enhanced by the addition of citrate ions in water solution. A sensitive luminescence enhancement system was developed for the determination of citrate ions on ...

In the title compound, C(17)H(15)NO(2), the dihedral angle between the quinoline and benzene ring systems is 62.17 (1)°. In the crystal, zigzag chains propagating in c are linked by C-H⋯O hydrogen bonds, and weak C-H⋯π inter-actions link the chains.