Globalization has affected the organizations in different aspects such as structure, architecture, internal/external strategies and sourcing management. Outsourcing is one of the recent business strategies used to provide IT needs via external agents. The relationship between the service buyer and provider companies is a constituent playing a significant role in IT outsourcing success or failur...

Supply chain disruptions significantly impact businesses worldwide. Many organizations work towards improving flexibility so as to prepare for such disruptions and maintain competitive advantage. This research effort examines four activities that are associated with the contingency planning process to determine which, if any, of these processes are ultimately supportive of organizational flexib...

Inter-organizational cost management is a strategic cost management approach to managing costs that span organizational boundaries in supply chains. Drawing on the resourcebased view of the firm, we develop a model to predict which inter-related resources might enable companies to manage inter-organizational costs. We test this model using a survey of managerial accountants whose organizations ...

To remain competitive or to simply survive in today’s highly dynamic environments, organizations often need to act rapidly. Top managers deal with urgent issues and must improvise. The role that information systems (IS) play in facilitating improvisation is critical to the organization’s internal processes and market performance. This research-in-progress paper reviews the organizational improv...

By drawing together the implications from several streams of IS research, addressing the critical research question posed extensively in IS literature, this study identifies the antecedents of individual’s behavioral and normative beliefs that shape intentions to use Business Intelligence Systems (BIS), explaining how those internal motivations are formed. Our comprehensive model of antecedents...

The electronic markets hypothesis holds that information technology use influences the dismantling of vertical firm boundaries because of reductions in the cost of transactions between firms. Anecdotal evidence of merger and alliance activity for information goods producing firms seems to be at odds with these predictions of an IT-driven rise in vertical market coordination structures. An inter...

RHO GTPases, members of the RAS superfamily of small GTPases, are adhesion and growth factor–activated molecular switches that play important roles in tumor development and progression. When activated, RHO-family GTPases such as RAC1, CDC42, and RHOA, transmit signals by recruiting a variety of effector proteins, including the protein kinases PAK, ACK, MLK, MRCK, and ROCK. Genetically induced l...