نتایج جستجو برای: 6 hydroxydopamine

تعداد نتایج: 956333  

2017
Chen-Tao Wang Cheng-Jie Mao Xiao-Qi Zhang Cai-Yi Zhang Dong-Jun Lv Ya-Ping Yang Kai-Lin Xia Jun-Yi Liu Fen Wang Li-Fang Hu Guang-Yin Xu Chun-Feng Liu

Background Although pain is one of the most distressing non-motor symptoms among patients with Parkinson's disease, the underlying mechanisms of pain in Parkinson's disease remain elusive. The aim of the present study was to investigate the role of serotonin (5-hydroxytryptamine) in the rostral ventromedial medulla (RVM) and spinal cord in pain sensory abnormalities in a 6-hydroxydopamine-treat...

Journal: :Hypertension 1992
E C Fletcher J Lesske J Culman C C Miller T Unger

We have previously described a rat model that responds to repetitive episodic hypoxia (FiO2 nadir 3-5% for 12 seconds every 30 seconds for 7 hr/day for 35 days) with chronic increase in arterial blood pressure. The purpose of the current study was to determine if peripheral sympathetic nervous system denervation blocks this persistent blood pressure elevation. Chemical sympathetic denervation w...

Journal: :Heliyon 2023

Parkinson's disease (PD) is characterized by a myriad of symptoms, encompassing both motor disabilities and cognitive impairments. Recent research has shown that abscisic acid (ABA) phytohormone found in various brain regions several mammals exhibits neuroprotective properties. To investigate the effects ABA on disorders, mouse model PD was utilized. The administration 6-hydroxydopamine (6-OHDA...

Journal: :Circulation research 1976
P J Kadowitz D S Knight R G Hibbs J P Ellison P D Joiner M J Brody A L Hyman

We studied the effects of 5- and 6-hydroxydopamine on adrenergic neurotransmission, fluorescence histochemistry, and nerve terminal ultrastructure in the canine pulmonary vascular bed. Fluorescence histochemistry on stretched preparations and sections of intrapulmonary artery and vein demonstrated that these vessels are well supplied with adrenergic nerves electron microscopy revealed adrenergi...

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