Non-Hodgkin's lymphoma (NHL) is a group of cancers that arise in the white blood cells. NHL is increasing rapidly in the U.S. and elsewhere in the industrialized world. In the year 1950, 5.9 Americans per 100,000 were diagnosed with non-Hodgkin's lymphoma. In 1985, the incidence (occurrence) rate of this disease had risen to 13.1 per 100,000.[1] By 1991, the incidence rate had reached 15.1 per ...

Communication between persons who trust each other differs from that between those who do not. A new conceptualization of trust is offered, drawing from game theory, credibility research, sensitivity/ encounter groups, and studies of generalized expectations of trustworthiness, which makes an important distinction between the cognitive state of iiust and trusting behaviors. Trusting behavior oc...

Abstract. Objective: The authors examined factors predicting college students’ use of tanning beds. Participants and Methods: Undergraduate students (N = 745) at a large Northeastern university participated in the study by answering a survey measuring tanning behavior and other psychosocial variables, including sensation seeking, self-esteem, tanning image beliefs, and friends’ tanning bed use....

Betulinic acid (BA), a plant derived triterpenoid, isolated from various sources shows cytotoxicity in cell lines of melanoma, neuroectodermal and malignant brain tumors. Chronic myelogenous leukemia (CML) is characterized by Philadelphia chromosome (Bcr-Abl), a molecular abnormality leading to the intrinsic tyrosine kinase activity that provides growth and survival advantage to the cells. Pres...

Natural polyphenols have been observed to possess antiproliferative properties. The effects, including apoptotic potential of bioactive phenolic compounds, caffeic acid (CA) and its derivative caffeic acid phenethyl ester (CAPE), on cell proliferation and apoptosis in human head and neck squamous carcinoma cells (HNSCC) line (Detroit 562) were investigated and compared. Cancer cells apoptosis r...

BACKGROUND Inositol hexakisphosphate (IP6), a naturally occurring polyphosphorylated carbohydrate, has been reported to have significant in vivo and in vitro anticancer activity against numerous tumors. However, the molecular mechanism of the anticancer effect of IP6 has not been fully elucidated. MATERIALS AND METHODS Using K-562 human leukemia cells we analysed the induction of the erythroi...

Chemotherapy is a common treatment for leukemia. Ruthenium complexes have shown potential utility in chemotherapy and photodynamic therapy. The identification of new chemotherapeutics agents is critical for further progress in the treatment of leukemia. Ruthenium complexes generally have lower toxicities compared to cisplatin attributed to their specific accumulation in cancer tissues. Based on...

The effective microorganism (EM-X) fermentation extract is derived from rice bran and seaweed extract. It has been shown to possess anti-oxidation activity both in vitro and in vivo. To our knowledge, the possible in vitro anti-cancer potential of EM-X has not been demonstrated. Here we showed that the double concentrate of EM-X (EM-X2) at concentrations of 20-30% by volume, had growth inhibito...