Introduction The GRASE (GRadient And Spin Echo) pulse sequence was proposed about two decades ago for T2-weighted imaging. GRASE suffers however from image ghosting due to the T2-modulation of the data. A vertical GRASE pulse sequence (vGRASE) was for that reason later introduced by Oshio, in which the EPI trains, following each RF echo, were modified to cover each a vertical instead of a horiz...

Fig. 3. DWSI of rat brain using (a) DW-EPSI and (b) DW-LSEPSI. The left images show NAA maps and the right graphs show average spectra in the red rectangles in the left images. Yellow lines in the left images show edges of a rat head. (c) ADC map of NAA using DW-LSEPSI. Color represents ADC value. Fig. 1. Sequence diagram of DW-LSEPSI. Diffusion-weighted Line-scan Echo-planar Spectroscopic Imag...

Enhanced glucose flux via the hexosamine biosynthesis pathway (HNSP) has been implicated in insulin resistance. We measuredl-glutamine:d-fructose-6-phosphate amidotransferase activity (GFAT, a rate-limiting enzyme) and concentrations of UDP- N-acetyl hexosamines (UDP-HexNAc, major products of HNSP) in muscle and liver of growth hormone (GH)-deficient male dwarf (dw) rats. All parameters measure...

Synthesis of single-wavelength temporal phase-shifting algorithms (PSA) for interferometry is well-known and firmly based on the frequency transfer function (FTF) paradigm. Here we extend the single-wavelength FTF-theory to dual and multi-wavelength PSA-synthesis when several simultaneous laser-colors are present. The FTF-based synthesis for dual-wavelength (DW) PSA is optimized for high signal...

Growing tumors are hypoxic and respond to microenvironmental stress through increased expression of the hypoxia inducible factor-1alpha (HIF-1alpha) transcription factor, resulting in an adaptive switch to glycolytic metabolism, angiogenic signaling, survival, and metastasis. HIF-1alpha expression is associated with tumor resistance to cytotoxic therapy and inferior patient outcomes. Pancreatic...

 Recently, the nutritional requirements of marine finfish larvae have received considerable attention, and studies have shown that docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and arachidonic acid (ARA) affects the growth and survival of marine finfish larvae. This study investigated the effects of different Artemia enrichments containing variable amounts of DHA and EPA on the gro...

The interaction mechanism between transverse domain walls TDWs in Permalloy nanowires and artificially patterned traps is studied using high-sensitivity spatially resolved magneto-optical Kerr effect measurements and numerical simulations. T-shaped trap geometries are considered, where a DW traveling in the horizontal arm is pinned by the vertical arm. Pinning strengths as well as potential ene...

A data warehouse (DW) provides information from external data sources for analytical processing, decision-making, and data mining tools. External data sources are autonomous, i.e. they change over time, independently of a DW. Therefore, the structure and content of a DW has to be periodically synchronized with its external data sources. This synchronization concerns DW data as well as schema. C...

Developing a data warehouse (DW) is a complex, time consuming and prone to fail task. Different DW models and methods have been presented during the last few years. However, none of them addresses the whole development process in an integrated manner. In this paper, we present a DW development method, based on the Unified Modeling Language (UML) and the Unified Process (UP), which addresses the...