Octyl- and nonylphenols in the environment have been proposed to function as estrogens. To gain insight into their structural essentials in binding to the estrogen receptor, a series of phenols with saturated alkyl groups at the para position, HO-C6H4-CnH2n+1 (n = 0-12), were examined for their ability to displace [3H]17beta-estradiol in the recombinant human estrogen receptor, which was expres...

Although cocaine is typically the second-most identified drug of abuse in drug-testing programs, there is surprisingly little quantitative information on excretion patterns following different routes of administration. This report details the urinary excretion and terminal elimination kinetics for cocaine and eight metabolites [benzoylecgonine (BZE), ecgonine methylester (EME), norcocaine (NCOC...

It becomes obvious that fat tissue is not just storage of excess carbohydrate. It is a regenerative complex supporting from the skin surface to deeper organs comprising adult stem cells as well as high energy resource related with tissue repair and regeneration. Fat grafting technique, which has been performed for more than hundred years, is utilized to improve defects of facial contour, fat at...

training levels. Eur J Radiol 2007;64:285–95. 9. Shinagawa N, Yamazaki K, Onodera Y, et al. Factors related to diagnostic sensitivity using an ultrathin bronchoscope under CT guidance. Chest 2007;131:549–53. 10. Vincent BD, Fraig M, Silvestri GA. A pilot study of narrow-band imaging compared to white light bronchoscopy for evaluation of normal airways and premalignant and malignant airways dise...

This paper develops a new approach to an old important and difficult problem: security planning in power system operations. The complexity of the problem is due primarily to two factors: (i) the large number of contingencies that need to be analyzed make it computationally intractable for real-time operations, and (ii) the problem has many solutions, and the global optimum is likely to be much ...

by Olivia Middleton A Low-fat Diet Containing Heated Soybean Oil Promotes Hyperglycemia in C57BL/6J Mice Introduction: The metabolic effects of consuming mildly oxidized lipids as compared to highly oxidized lipids are not well documented. Consumption of highly oxidized polyunsaturated fatty acids, even in a low-fat diet, may be a threat to one’s health. Previous studies in our lab have shown t...

Objective: Major depression is a common mental illness with usual onset in adolescence and young adulthood. Brain imaging studies using functional magnetic resonance imaging (fMRI) have reported altered functional connectivity in depressed patients compared to healthy controls, which normalize with effective treatment. Escitalopram is an antidepressant commonly used to treat depression, but wit...

BACKGROUND Though Mica, a thin and sheet like mineral, has been used as a mineral medicine for treatment of bleeding, dysentery and inflammation in traditional medicine including Ayurveda, the biological evidences of Mica were not clearly elucidated so far. Thus, in the present study, the antitumor mechanism of particled Mica (STB-HO) was examined in colorectal cancers. METHODS Athymic nude m...

Objective: Major depression is a common mental illness with usual onset in adolescence and young adulthood. Brain imaging studies using functional magnetic resonance imaging (fMRI) have reported altered functional connectivity in depressed patients compared to healthy controls, which normalize with effective treatment. Escitalopram is an antidepressant commonly used to treat depression, but wit...

A short range force constant model (SRFCM) has been applied for the first time to investigate the phonons in RMnO3 (R = Pr, Eu, Tb, Dy, Ho) perovskites in their orthorhombic phase. The calculations with 17 stretching and bending force constants provide good agreement for the observed Raman frequencies. The infrared frequencies have been assigned for the first time. PACS Codes: 36.20.Ng, 33.20.F...