Corresponding author: Przemysław Węglarz MD, 1 Department of Cardiology, Silesian University of Medicine, 45/47 Ziołowa St, 40-635 Katowice, Poland, phone: +48 600 467 332, e-mail: [email protected] Received: 23.01.2017, accepted: 13.02.2017. Neointima development in externally stented saphenous vein grafts. Progress in medicine is good for the patient: why not use total arterial revasculariza...

To whom the correspondence should be addressed: Gunnar Schulte, Section of Receptor Biology & Signaling, Dept. Physiology & Pharmacology, Karolinska Institutet, S-171 77 Stockholm, Sweden. Tel.: +46-8-52487933; Fax: +46-8-341280; E-mail: [email protected] Rami N. Hannoush, Department of Early Discovery Biochemistry, Genentech, 1 DNA Way, South San Francisco, California 94080, United States. ...

I. The Alzheimer Disease Puzzle 466 A. The amyloid cascade hypothesis 466 B. Moving towards more comprehensive theories for AD 466 C. The importance of tau 467 II. Proteolysis Involved in Multiple Scenarios for Alzheimer Disease 467 A. Proteolytic processing of the APP 467 B. General disturbances of the endolysosomal-phagocytotic system in AD neurons 468 III. Heterogeneity of the Amyloid A Pept...

The TyrR protein of Escherichia coli K12 is a homodimer containing 513 amino acids/subunit. This protein is important in the transcriptional regulation of several genes whose protein products catalyze steps in aromatic amino acid biosynthesis or transport. Methods were developed for efficiently purifying the TyrR protein to apparent homogeneity. We analyzed the pattern of cleavage of the TyrR p...

BACKGROUND AND OBJECTIVES The current allocation algorithm for deceased donor kidney transplantation takes into consideration HLA mismatches at the ABDR loci but not HLA mismatches at other loci, including HLA-DQ. However, the independent effects of incompatibilities for the closely linked HLA-DQ antigens in the context of HLA-DR antigen matched and mismatched allografts are uncertain. We aimed...

In this paper we complete a classification of finite linear spaces S with line size at most 12 admitting a line-transitive point-imprimitive subgroup of automorphisms. The examples are the Desarguesian projective planes of orders 4, 7, 9 and 11, two designs on 91 points with line size 6, and 467 designs on 729 points with line size 8.

AKI YAMADA,1 SUSUMU OHYA,2 MASARU HIRANO,2 MINORU WATANABE,2 MICHAEL P. WALSH,3 AND YUJI IMAIZUMI1 1Department of Pharmacology and Therapeutics and 2Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan; and 3Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Ca...