The bacterial strain RB1 has been isolated by enrichment cultivation with 2,4-dinitrophenol as the sole nitrogen, carbon, and energy source and characterized, on the basis of 16S rRNA gene sequence comparison, as a Rhodococcus species closely related to Rhodococcus opacus. Rhodococcus sp. strain RB1 degrades 2,4-dinitrophenol, releasing the two nitro groups from the compound as nitrite. The rel...

Oxidative phosphorylation has been studied in mitochondria and homogenates of six normal and five solid neoplastic rat tissues by determination of P :0 and control ratios and through the use of fluoride and dinitrophenol. In mitochondria prepared from the eleven tissues, P :O ratios with glutamate varied from 2.2 to 2.8, and with succinate from 1.1 to 2.0. Similar control of respiration by phos...

Background: Phenol and its derivatives like dinitrophenol and pentachlorophenol (carbolic acid) are widely used as insecticides, but they are very toxic substances. Phenol is a general protoplasmic poison with corrosive local effects that denature proteins. Poisoning with phenol compounds may occur by ingestion, inhalation, and absorption through skin. In this report we presented the toxicity...

Abstract. To investigate the composition, variation, and sources of nitrated phenols (NPs) in winter Beijing, gas-phase NPs were measured by a chemical ionization long time-of-flight mass spectrometer (CI-LToF-MS). A box model was applied to simulate secondary formation process NPs. In addition, primary resolved non-negative matrix factorization (NMF) model. Our results showed that contributed ...

The Front Cover represents how purple bacterial cells utilized in biohybrid electrochemical systems hit, or miss, their “target electrode” with photo-induced electrons depending on the concentration of dinitrophenol at which they are exposed. More information can be found Research Article by L. D. de Moura Torquato et al.

Decreased uncoupling protein (UCP)3 is associated with insulin resistance in muscle of pre-diabetic and diabetic individuals, but the function of UCP3 remains unclear. Our goal was to elucidate mechanisms underlying the negative correlation between UCP3 and insulin resistance in muscle. We determined effects of physiologic UCP3 overexpression on glucose and fatty acid oxidation and on mitochond...

INTRODUCTION Earlier work from this laboratory (9, 11) has shown that the addition of fluoride permits isotonic homogenates of the Walker 256 carcinosarcoma and the Flexner-Jobling carcinoma to oxidize to an appreciable extent the various inter mediates of the tricarboxylic acid cycle when sup plemented with adenosinetriphosphate (ATP). From data on phosphate balance (11, 12), it has been sugge...

Rhodococcus opacus HL PM-1 utilizes 2,4,6-trinitrophenol (picric acid) as a sole nitrogen source. The initial attack on picric acid occurs through two hydrogenation reactions. Hydride transferase II (encoded by npdI) and hydride transferase I (encoded by npdC) are responsible for the hydride transfers. Database searches with the npd genes have indicated the presence of a putative transcriptiona...

Changes in phosphate metabolism were explored in discs from tobacco (Nicotiana tabacum) leaves of three contrasting types: green leaves which were fully expanded and attached to the plant, leaves which had yellowed following excision and dark starvation, and leaves which had yellowed while attached to the plant. 2,4-Dinitrophenol at 10(-5)m stimulated the respiration rate of discs from green an...