نتایج جستجو برای: 3h pyrazolo43 aacridin 11 carbonitriles

تعداد نتایج: 404568  

Journal: : 2023

Nghiên cứu này nhằm đánh giá ảnh hưởng của các phương pháp kích thích khác nhau đến hiệu quả sinh sản ốc bươu đồng. Thí nghiệm được bố trí trong bể có thước (1m × 1m 1 m), mật độ 30 cá thể ốc/m2 (tỷ lệ đực:cái bằng nhau) và mực nước ban đầu là 40 cm. Mỗi thức lặp lại 3 lần với như sau: 1) Tăng 50% nước, kết hợp phơi bóng râm 2 giờ (A50-2h); 2) (A50-3h); 3) 4 (A50-4h); 4) Giảm 75% (D75-2h); 5) (...

Journal: :British journal of anaesthesia 1999
N Kumar D Smart S Mason A T McKnight D J Rowbotham D G Lambert

Our aim was to identify the nociceptin receptor and its endogenous ligand, nociceptin, in human peripheral tissue. Synovial tissue was obtained from 11 patients (ASA I-III, 66-84 yr) undergoing elective total knee replacement. Synovial fluid was obtained from another 10 patients (ASA I-III, 57-81 yr). Fluid was mixed with trifluoroacetic acid and the tissue with isopentone before freezing at -7...

Journal: :American journal of physiology. Endocrinology and metabolism 2004
Yuka Fujimoto E Patrick Donahue Masakazu Shiota

Hepatic glucose fluxes and intracellular movement of glucokinase (GK) in response to increased plasma glucose and insulin were examined in 10-wk-old, 6-h-fasted, conscious Zucker diabetic fatty (ZDF) rats and lean littermates. Under basal conditions, plasma glucose (mmol/l) and glucose turnover rate (GTR; micromol.kg(-1).min(-1)) were slightly higher in ZDF (8.4 +/- 0.3 and 53 +/- 7, respective...

Journal: :The Journal of pharmacology and experimental therapeutics 1989
L Mei J Lai W R Roeske C M Fraser J C Venter H I Yamamura

The muscarinic receptors in a B82 cell line which were transfected with the rat m1 muscarinic receptor gene (cTB10 cells) were studied by using radioligand binding assays. Their possible coupling to the hydrolysis of inositol lipids and cyclic AMP formation were also investigated. [(-)-[3H]Quinuclidinyl benzilate [(-)-[3H]QNB] binding to the intact cTB10 cells was saturable and displaceable by ...

2002

Simultaneous profiles of the transient tracers sulfur hexafluoride (SF6), 3H-3He, and the chlorofluorocarbons CFC-11 and CFC-12 were measured in Lake Issyk-Kul, a large, deep lake in Kyrgyzstan. Apparent water ages derived from these measurements suggest rapid mixing, with a deepwater renewal rate .10% yr21 at 650 m depth. SF6 and 3H3He ages agree reasonably well, whereas CFC ages are significa...

Journal: :Experimental Neurology 2021

Parkinson's disease (PD) is characterized by Lewy body and neurite pathology associated with dopamine terminal dysfunction. Clinically, it motor slowing, rigidity, tremor. Postural instability pain are also features. Physical exercise benefits PD patients - possibly promoting neuroplasticity including synaptic regeneration. In a parkinsonian rat model, we test the hypotheses that exercise: (a) ...

Journal: :Organic & biomolecular chemistry 2015
Adel S Girgis Siva S Panda Aladdin M Srour Hanaa Farag Nasser S M Ismail Mohamed Elgendy Amal K Abdel-Aziz Alan R Katritzky

3D-pharmacophore and 2D-QSAR modeling studies describe the anti-oncological properties of spiro-alkaloids. The dispiro[2H-indene-2,3'-pyrrolidine-2',3''-[3H]indole]-1,2''(1''H, 3H)-diones 20-38 were prepared via 1,3-dipolar cycloaddition reactions of azomethine ylides (generated in situ via decarboxylative condensation of isatins 7-9 with sarcosine 10) and 2-(arylmethylidene)-2,3-dihydro-1H-ind...

Journal: :Journal of lipid research 2004
Thomas A Spencer Pingzhen Wang Dansu Li Jonathon S Russel David H Blank Jarkko Huuskonen Phoebe E Fielding Christopher J Fielding

Eight analogs of cholesterol (1) containing a benzophenone group have been synthesized as prospective photoaffinity labels for studies in cellular sterol efflux and HDL formation. Six of these compounds (4-9) have the photophore replacing different portions of the cholesterol alkyl side chain, and two (10 and 11) have it attached via nitrogen at carbon 3. The suitability of these analogs as cho...

Journal: :Journal of Applied Phycology 2022

Cyanobacterial alkaline phosphatases (APases) play a key role in organophosphate utilization freshwater. Tracking the distribution of APases can provide insights into physiological response phytoplankton to phosphorus nutrition. Extracellular APase PhoX, one three prokaryotic families, is important for utilization. Because existing methods only give information on bulk activity, specific contri...

2001
V. Guzey K. Saito M. Strikman K. Tsushima

We study shadowing and antishadowing corrections to the flavor nonsinglet structure function F 3He 2 − F 3H 2 and show that the difference between the one-particle density distributions of 3He and 3H plays an important role at very small x. We find that the flavor non-singlet structure function in these mirror nuclei is enhanced at small x by nuclear shadowing, which increases the nuclear Gottf...

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