BACKGROUND External beam radiotherapy (EBRT) for retinoblastoma has traditionally been done with conventional radiotherapy techniques which resulted high doses to the surrounding normal tissues. CASE REPORT A 20 month-old girl with group D bilateral retinoblastoma underwent intensity modulated radiotherapy (IMRT) to both eyes after failing chemoreduction and focal therapies including cryother...

Introduction: The rate of cardiac diseases have increased among patients who underwent radiotherapy for left-sided breast cancer. The study’s aim was evaluate the dose to organs at risk in free-breathing 3-dimensional conformal (FB-3DCRT) against 3-dimensional conformal deep inspiration breath-hold (3DCRT-DIBH) in patients with left-sided breast cancer. Ma...

PURPOSE The purpose of this study is to compare the dosimetric differences among volumetric modulated arc therapy (VMAT), fixed-field intensity modulated radiotherapy (IMRT) and three-dimensional conformal radiotherapy (3D-CRT) for the preoperative locally advanced rectal cancer (LARC). METHODS Ten LARC patients treated in our department using the simultaneous escalate strategy were retrospec...

PURPOSE The purpose is to evaluate the feasibility, efficacy, and the toxicity of three-dimensional conformal radiotherapy (3DCRT) in patients with advanced hepatocelluar carcinoma (HCC) and inferior vena cava tumor thrombosis (IVCTT). METHODS Between 2007 and 2012, in a retrospective way, 9 patients (median age 69 years) with advanced HCC and IVCTT unfit for surgery, radiofrequency ablation,...

PURPOSE The present study was undertaken to determine the effect of radiation dose on biochemical control and morbidity in prostate cancer patients. MATERIALS AND METHODS Between 1995 and 2003, 360 patients with T1-T3b prostate cancer were treated in a sequential radiation dose escalation trial from 66.0 to 82.6 Gy. These patients were prospectively assigned to 1 of 3 prognostic groups accord...

Background: 3DCRT (three-dimensional conformal radiotherapy) and IMRT (intensity-modulated radiotherapy) has provided us with tools to delineate the radiation dose distribution of tumor targets. However, the precision of radiation can be compromised by respiratory motion, which usually limits the geometric and dosimetric accuracy of radiotherapy. The purpose of this study is to evaluate the imp...

Cervical cancer radiotherapy on the Linac aircraft uses a 6 MV energy photon beam with 3 Dimension Conformal Radiotherapy (3DCRT) and Intensity Modulation Radiation Therapy (IMRT) techniques. planning 3DCRT IMRT techniques is then compared by analyzing dose distribution or target volume (PTV) coverage through Conformity Index (CI) Homogeneity (HI) Organ At Risk (OAR) where risk organ that consi...

Since the introduction of 3-dimensional conformal radiotherapy (3DCRT), new radiotherapy techniques have expanded the indication of radiotherapy for the treatment of hepatocellular carcinoma (HCC), from the hitherto palliative to a now curative-intent purpose. Intensity-modulated radiotherapy (IMRT), currently the most advanced radiotherapy technique, is considered an attractive option for the ...

BACKGROUND Except for early T1,2 N0 stages, the prognosis for patients with oral cavity cancer (OCC) is reported to be worse than for carcinoma in other sites of the head and neck (HNC). The aim of this work was to assess disease outcome in OCC following IMRT.Between January 2002 and January 2007, 346 HNC patients have been treated with curative intensity modulated radiation therapy (IMRT) at t...

BACKGROUND The accuracy of dose calculation is crucial to the quality of treatment planning and, consequently, to the dose delivered to patients undergoing radiation therapy. Current general calculation algorithms such as Pencil Beam Convolution (PBC) and Collapsed Cone Convolution (CCC) have shortcomings in regard to severe inhomogeneities, particularly in those regions where charged particle ...