La fluctuación petrolera tiene una incidencia significativa en la economía mundial, puesto que repercute sobre los ingresos perciben países exportadores e influye costos de producción importadores. Los factores políticos, económicos, fenómenos naturales y bélicos provocan movimientos inesperados el precio del crudo. Este trabajo establece relación entre petróleo PIB Ecuador con finalidad presen...

No AccessEngineering NotesNote on the Non-CO2 Mitigation Potential of Hybrid-Electric Aircraft Using “Eco-Switch”Malte Niklaß, Benjamin Lührs and Majed SwaidMalte NiklaßDLR, German Aerospace Center, 21079 Hamburg, Germany*Scientist, Air Transportation Systems; .Search for more papers by this author, LührsDLR, Germany†Scientist, author SwaidDLR, Germany‡Scientist, authorPublished Online:12 Sep 2...

Population Health ManagementVol. 24, No. 3 Points of ViewOpen AccessCreative Commons licenseSocial Intervention by the Numbers: Evidence Behind Specific Public Guidelines in COVID-19 PandemicMichael P. Savage, David L. Fischman, and Mamas A. MamasMichael SavageAddress correspondence to: Michael MD, Thomas Jefferson University, 111 South 11th Street, Suite 6210, Philadelphia, PA 19107, USA E-mai...

Open AccessCCS ChemistryCOMMUNICATION1 May 2021Copper-Catalyzed Enantioselective Trifluoromethylthiolation of Secondary Propargyl Sulfonates Xing Gao, Yu-Lan Xiao, Shu Zhang, Jian Wu and Xingang Zhang Gao Key Laboratory Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute Organic University Chinese Academy Sciences, 200032 Google Scholar More articles by th...

For five decades, the semiconductor industry has distinguished itself by the rapid pace of improvement in miniaturization of electronics products—Moore’s Law. Now, scaling hits a brick wall, a paradigm shift. The industry roadmaps recognized the scaling limitation and project that packaging technologies will meet further miniaturization needs or a.k.a “More than Moore”. This paper presents pack...

The adenylate cyclase hemolysin toxin (ACT) is one of the main virulence factors in Bordetella pertussis. It was discovered in 1973 by Wolff and Cook as a contaminant in vaccine formulations against this microorganism. It belongs to the family of toxins that form pores at the plasma membrane of target cells and reaches the highest expression during the virulent phase of the bacteria. This toxin...

The estrogen receptor (ER), like other members of the nuclear receptor superfamily, possesses two separate transcriptional activation functions, AF-1 and AF-2. Although a variety of coactivators and corepressors of AF-2 have been identified, less is known of the mechanism of action of AF-1. We have used the yeast two-hybrid system to isolate a cDNA coding for a protein that binds specifically t...