BACKGROUND Hypertrophic lichen planus (HLP) classically involves shin and ankles and is characterized by hyperkeratotic plaques and nodules. Prurigo nodularis (PN) is a chronic neurodermatitis that presents with intensely pruritic nodules. Histopathology of HLP and PN demonstrate epidermal hyperplasia, hypergranulosis, and compact hyperkeratosis. The dermis shows vertically arranged collagen fi...

Projection neurons (PNs) in the locust antennal lobe exhibit odor-specific dynamic responses. We studied a PN population, stimulated with five odorants and pulse durations between 0.3 and 10 s. Odor representations were characterized as time series of vectors of PN activity, constructed from the firing rates of all PNs in successive 50 ms time bins. Odor representations by the PN population can...

Songbirds learn and produce complex sequences of vocal gestures. Adult birdsong requires premotor nucleus HVC, in which projection neurons (PNs) burst sparsely at stereotyped times in the song. It has been hypothesized that PN bursts, as a population, form a continuous sequence, while a different model of HVC function proposes that both HVC PN and interneuron activity is tightly organized aroun...

A labeling f on a graph G on n vertices is called a prime labeling if f is a bijection from the vertex set V (G) to {1, 2, · · · , n} such that f(x) and f(y) are coprime if x and y are adjacent. It was shown by Sundaram et al. [1] that the planar grid Pm × Pn has a prime labeling if m ≤ n and n is a prime. In this paper it is proved that the following grids have a prime labeling: (i) Pn+1 × Pn+...

AIM To investigate the effects of Panax notoginseng (PN) on microvascular injury in colitis, its mechanisms, initial administration time and dosage. METHODS Dextran sodium sulfate (DSS)- or iodoacetamide (IA)-induced rat colitis models were used to evaluate and investigate the effects of ethanol extract of PN on microvascular injuries and their related mechanisms. PN administration was initia...

Hops, an essential beer ingredient, are a source of prenylflavonoids, including 8-prenylnaringenin (8-PN), one of the most potent phytoestrogens. Because 8-PN concentrations in beers are generally low, its health effects after moderate beer consumption were considered negligible. However, human intestinal microbiota may activate up to 4 mg/L isoxanthohumol (IX) in beer into 8-PN. Depending on i...

terminal drought stress during grain filling period has recently become more common in the semiarid mediterranean regions, where wheat (triticum aestivum) is grown as an important winter cereal crop. the objective of this experiment was to study the effect of terminal drought stress on grain yield, gas exchange variables, and some physiological traits of nine bread wheat cultivars. an experimen...

The cerebellar cortex is centrally involved in motor coordination and learning, and its sole output is provided by Purkinje neurons (PNs). Growth of PN dendrites and their major synaptic input from granule cell parallel fiber axons takes place almost entirely in the first several postnatal weeks. PNs are more vulnerable to cell death than most other neurons, but the mechanisms remain unclear. W...