Tachyphylaxis may have contributed to the failure of the motilide ABT-229 [N-ethyl, N-methyl 4'' deoxy erythromycin (EM)-B enolether] in clinical trials. We compared the desensitizing potency of structurally related motilides [EM-A, EM-A enolether (ME4), N-ethyl, N-methyl EM-A (ME36), EM-B enolether (ME67), N-ethyl, N-methyl EM-A enolether (EM523), ABT-229 and 4'' deoxy EM-A enolether (KOS1326)...

OBJECTIVE To retrospectively determine the sensitivity of preoperative CT in the detection of small (≤ 10 mm) colorectal liver metastasis (CRLM) nodules in patients undergoing liver resection. METHODS The institutional review board approved the study and waived informed consent. We included 461 pathologically confirmed CRLM nodules in 211 patients (including 71 women; mean age, 66.4 years) wh...

AIMS Patients with atrial fibrillation (AF) consider the related symptoms disruptive to their quality of life (QoL). This study aimed to evaluate the impact of the control of symptomatic paroxysmal AF (PAF) on QoL. METHODS AND RESULTS Patients with symptomatic PAF were treated for 48 weeks with open-label flecainide acetate controlled release (Flec CR). Quality of life was assessed by SF-36 a...

Economic Models and Generalized Games 229 4.

As computers become ubiquitous, they are increasingly used in safety critical environments. Since many safety critical applications are real-time systems, automated analysis technique of real-time properties is desirable. Most widely used automated analysis techniques are based on state space exploration. Automatic analysis techniques based on state space exploration suffer from the state space...

(sinα)/α [113]. 0 [210]. 1 [222]. 1/π [188, 189]. 1/π [217, 189]. 10, 000 [49]. 10, 000, 000 [134]. 16 [197]. 2 [52, 55]. 2 + 2 [209]. 2, 000 [35]. 2, 576, 980, 370, 000 [211]. 29, 360, 000 [98]. 2H2 [221]. b [176]. e [99, 93, 56, 34, 111, 28, 35, 36, 209, 12, 54]. e−(π/2) = i [13]. GL(n, Z) [96]. n [141, 96, 133]. φ [187, 194]. π [228, 183, 84, 135, 97, 136, 169, 227, 31, 98, 99, 24, 20, 168, ...

http://rsw.sagepub.com/content/17/2/229 The online version of this article can be found at: DOI: 10.1177/1049731506296826 2007 17: 229 Research on Social Work Practice Sanders II Samuel A. MacMaster, Jenny L. Jones, Randolph F. R. Rasch, Sharon L. Crawford, Stephanie Thompson and Edwin C. HIV in the Southern United States Evaluation of a Faith-Based Culturally Relevant Program for African Ameri...

INTRODUCTION .......................................................................................................................................................223 GENOMIC ORGANIZATION OF HCV..................................................................................................................223 GENOMIC HETEROGENEITY AND CLASSIFICATION SYSTEMS ......................................