Correspondence to: Don Poldermans, MD, PhD, Thoraxcentre, Department of Cardiology, Erasmus Medical Centre Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands; [email protected] _________________________ C oronary artery disease is the most common cause of congestive heart failure. More than 70% of the patients with heart failure symptoms have underlying coronary diseas...

Prostate cancer (PCa) remains a major health concern for the male population. Detection and primary diagnosis of PCa are based on digital rectal examination, serum prostate-specific antigen levels, and transrectal ultrasound (TRUS)-guided random biopsy. Moreover, the gold standard for detecting PCa, systematic biopsy, lacks sensitivity as well as grading accuracy. This review summarizes recent ...

To assess the influence of footwear on injury, we prospectively studied all injured children presenting to the Emergency Department of The Children's Hospital of Philadelphia during February, May, July, and October 1988. Information was collected concerning the type and characteristics of footwear worn and environmental factors. Comparisons were made between those involving and those not involv...

IgD is considered to be a recently-evolved Ig and a puzzling molecule, being previously found in all vertebrate taxa, except for birds. Although IgD likely plays an important role in vertebrate immune responses, the function of IgD in Nile tilapia (Oreochromis niloticus) is virtually unknown. In the present study, a membrane form of IgD (mIgD) heavy chains were cloned from the GIFT strain of Ni...

OBJECTIVE To learn about neck lacerations caused by skate blades in hockey. DESIGN A retrospective Web-based survey and follow-up of registered USA Hockey players. SETTING Three hundred twenty-eight thousand eight hundred twenty-one of 457 038 registered USA Hockey players with a current e-mail address were contacted and invited to participate in the survey. PARTICIPANTS Of 26 589 players...

Section: Immunobiology Human T-cell Leukemia Virus Type 2 produces a spliced antisense transcript encoding a protein that lacks a classical bZIP domain but still inhibits Tax2-mediated transcription Short title: HTLV-2 antisense transcript Marilène Halin, Estelle Douceron 6, 7, , Isabelle Clerc, Chloé Journo 6, 7, , Nga Ling Ko, Sébastien Landry, Edward L. Murphy, Antoine Gessain, Isabelle Lema...

tween industry funding and statistically significant pro-industry findings in medical and surgical randomized trials. CMAJ 2004; 170:477– 80. 22. Relman AS, Angell M. America’s other drug problem: how the drug industry distorts medicine and politics. New Repub 2002; 227:27– 41. 23. Krzyzanowska MK, Pintilie M, Tannock IF. Factors associated with failure to publish large randomized trials presen...

OBJECTIVE To investigate the anatomic symmetry of maxillary and mandibular posteriors in Indian subpopulation using cone beam computed tomography (CBCT). MATERIALS AND METHODS CBCT images of 246 patients that had at least one noncarious, posterior tooth free of restorations in each quadrant were enrolled for retrospective analysis. A total of 3015 teeth (811 maxillary premolars, 845 mandibula...

Many pathogenic streptococci produce extracellular hyaluronan lyases which are thought to aid the spread of the organism in host tissues. In addition, several phages of group A streptococci are known to synthesize a bound form of hyaluronidase. It has been suggested that the function of this hyaluronidase is to facilitate penetration of the hyaluronan capsule by phage and thus to gain access fo...

Prostate cancer (PCa) remains a major health concern for the male population. Detection and primary diagnosis of PCa are based on digital rectal examination, serum prostate-specific antigen levels, and transrectal ultrasound (TRUS)-guided random biopsy. Moreover, the gold standard for detecting PCa, systematic biopsy, lacks sensitivity as well as grading accuracy. This review summarizes recent ...