نتایج جستجو برای: 3 np
تعداد نتایج: 1843892 فیلتر نتایج به سال:
Treatment of myocardial infarction (MI) with adipose-derived stem cells (ASCs) has produced promising results. Cyclosporine A (CsA) inhibits apoptosis by preventing the opening of mitochondrial permeability transition pores. A CsA nanoparticle emulsion (CsA-NP) has lower toxicity and higher efficiency as compared to CsA. In this study, we hypothesized that a combination of ASCs and CsA-NP would...
Impairments in mitochondrial energy metabolism are thought to be involved in many neurodegenerative diseases. The mitochondrial inhibitor 3-nitropropionic acid (3-NP) induces striatal pathology mimicking neurodegeneration in vivo. Previous studies showed that 3-NP also triggered autophagy activation and apoptosis. In this study, we focused on the high-mobility group box 1 (HMGB1) protein, which...
We study the question of whether the class DisjNP of disjoint pairs (A,B) of NPsets contains a complete pair. The question relates to the question of whether optimal proof systems exist, and we relate it to the previously studied question of whether there exists a disjoint pair of NP-sets that is NP-hard. We show under reasonable hypotheses that nonsymmetric disjoint NP-pairs exist, which provi...
زمینه و هدف: ویروس آنفلوانزا A یک پاتوژن تنفسی مهم است که باعث بیماری و مرگ و میر گسترده در طول اپیدمی‌های فصلی و پاندمی ها می‌شود. واکسن‌های رایج آنفلوانزا توانایی ایجاد ایمنی مؤثر در برابر سویه‌های مختلف ویروس آنفلوانزا را ندارند. طراحی واکسن‌های فراگیر با استفاده از آنتی‌ژن‌های حفاظت شده‌ی ویروس آنفلوانزا در جهت رفع این محدودیت می‌باشد. ناحیه بیرونی پروتئین M2 آنفلوانزا (M2e)، ساقه هماگلوتی...
P versus NP is considered as one of the most important open problems in computer science. This consists knowing answer following question: Is equal to NP? It was essentially mentioned 1955 from a letter written by John Nash United States National Security Agency. However, precise statement problem introduced independently Stephen Cook and Leonid Levin. Since that date, all efforts find proof fo...
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