نتایج جستجو برای: 3 diones
تعداد نتایج: 1811822 فیلتر نتایج به سال:
We have developed a new technology called multi-catalysis for the sequential one-pot synthesis of highly functionalized heterocycles. A practical and novel multi-component aniline-, self- and Brønsted acid-catalyzed selective process for the sequential one-pot synthesis of highly substituted 2-(2-hydroxy-aryl)-cyclopentane-1,3-diones, 3,9-dihydro-2H-cyclopenta[b]chromen-1-ones and 3,3-dimethyl-...
Based on principles of pharmacophore delineation and drug designing, compounds containing diketofunctionallity namely 1,2-bis[5-thiazolyl]ethane-1,2-diones were designed and synthesized as antiinflammatory agents. The compounds were evaluated in carrageenan-induced rat-paw edema method. G-3, G-6, G-17, G-20, G-23, G-22, L-708 and 906 showed good antiinflammatory activity. In addition as diketo ...
Due to the drawbacks of applying catalysts in the synthesis of α,β-unsaturated structure units and the importance of these materials, electrochemistry has been introduced as an efficient alternative.Therefore, herein a high-yield synthesis of 2-arylideneindan-1,3-diones is proposed. The procedure is carried out in propanol, using electrons as a green catalyst for generating propanol anion...
Orchids employing sexual deceit attract males of their pollinator species through specific volatile signals that mimic female-released sex pheromones. One of these signals proved to be 2-ethyl-5-propylcyclohexan-1,3-dione (chiloglottone1), a new natural product that was shown to be most important in the relations between orchids of the genus Chiloglottis, native to Australia, and corresponding ...
The formation of the benzo[a]pyrene (B[a]P) diones (B[a]P-1,6-dione, B[a]P-3,6-dione, B[a]P-6,12-dione) as the main products of oxidative degradation of B[a]P has been observed under atmospheric conditions in air particulate matter. Samples were collected at two different sites in Munich, Germany. Total B[a]P dione concentrations were determined by APCI/LC-MS and ranged between 8 and 605 pg m-3...
Two series of spiro[ [1]benzothiophene-3,2'-[1,3]thiazolidine]-2,4'-diones 5a-e and 6a-e were synthesized, characterized and evaluated for anticonvulsant activity. Reaction of [1]benzothiophene-2,3-dione (3) with certain arylamines afforded the corresponding Schiff bases 4a-e. Cyclization of 4a-e with thioglycolic or thiolactic acids brought about the target spiro compounds 5a-e and 6a-e respec...
Synthesis of 2-(2-hydroxy-3-amino)propyl derivatives of 4-alkoxy-6-methyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones (24-35) is described. The chlorides used in the above synthesis exist mainly in the cyclic forms (18, 20-23). Only chloride with benzhydryl substituent at the nitrogen atom of piperazine has the chain structure (19). Among the studied imides the most active analgesics in the "writh...
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