1. Hydrogen cyanide inhibited acetoacetate decarboxylase only when incubated with the enzyme in the presence of car-bony1 compounds. This resulted in an inhibitory synergism between hydrogen cyanide and carbonyl compounds. This synergism was used to investigate the comparative abilities of various carbonyl compounds to form Schiff’s bases at the active site of the enzyme. The order of effective...

Indium(III) triflate is found to be an effective catalyst for the benzannulation reactions of o-alkynylbenzaldehydes with enolisable aldehydes, ketones, 1,3-diketones and β-keto esters. The reactions produce naphthyl ketones through ring opening of adducts arising from the inverse electron demand Diels-Alder reactions between in situ generated isochromenylium cations and enols. The main feature...

A Pt(II)-catalyzed intramolecular chemo- and regioselective pentannulation/long-range 1,5-acyl migration reaction is described. This cascade cycloisomerization protocol produces a wide variety of benzofulvene diketones in good to excellent yields with exclusively the Z configuration of the exocyclic double bond of the final product. The (18)O isotope experiment together with (13)C NMR, HRMS, an...

This study presents our view of unconventional and conventional intramolecular hydrogen bonds (HBs) for some beta-diketones theoretically and experimentally. According to our results, the groups such as Phenyl and t-But in beta positions increase and CF3 group decrease IHB strength, respectively. For better understanding of the substitution effects, the compounds with similar and different subs...

quinolines, an important class of potentially bioactive compounds, have been synthesized by treatment of o-aminoarylketones and carbonyl compounds utilizing niobium (v) chloride / polyethylenglycole(nbcl5.peg) and niobium(v)chloride (nbcl5) as available and inexpensive catalysts. the quinoline derivatives were prepared in glycerol, an excellent solvent in terms of environmental impact, with hig...

condensation of aromatic aldehydes with benzoyl acetone under specified conditions yieldedtwo series of polycarbonyl compounds in which the keto group is attached to olefinic linkage.spectral and analytical data revealed the formation of an unsaturated triketone from pyridine-3-carbaldehyde and unsaturated diketone from furfural, salicylaldehyde and 2-hydroxynaphthaldehyde. analytical, ir, 1h n...

1,2-Diketones have been reacted in one-pot method with 1,2-diamines at room temperature with ZnO nanoparticles as a catalyst. ZnO nanoparticles as an available and reusable catalyst is used for the synthesis of Quinoxalinein improved yields.

oxidation of some benzoins to benziles is reported by using p-toluenesulfonic acid as aselective oxidation catalyst under solvent-free condition in high yield. the adjacent carbonylgroup is necessary for the oxidation of hydroxyl group in these compounds. the reaction iscarried out in a sand-bath at 100 °c with minimum by-products.