argyrophilic staining of nucleolar organizer regions (agnor) has been considered to be useful in the diagnosis and prognostic evaluation of different cutaneous tumors. in order to evaluate the role of the agnor technique in discriminating aggressive from non-aggressive basal cell carcinoma (bcc), paraffin-embedded histologic sections from 30 cases of aggressive bcc (bcc2) and 30 cases of non-ag...

Material and Methods: The present study was conducted on 40 specimens of breast carcinoma out of which 12 cases were of Grade II and 28 cases were of Grade III. Percentage positivity and scoring of Ki-67 and mean AgNOR count was done with relation to grades. Observations: Ki-67 positivity was seen in 12 cases with the percentage positivity of 2.33±5.516 in grade II and 9.67±7.671 in grade III t...

Argyrophilic staining of nucleolar organizer regions (AgNOR) has been considered to be useful in the diagnosis and prognostic evaluation of different cutaneous tumors. In order to evaluate the role of the AgNOR technique in discriminating aggressive from non-aggressive basal cell carcinoma (BCC), paraffin-embedded histologic sections from 30 cases of aggressive BCC (BCC2) and 30 cases of n...

  Background and Objectives: Uterine smooth muscle tumors are the most common human neoplasm .They are divided clinically as benign and malignant but there is  another group of  lesions which is difficult to place in these two categories ,so-called smooth  muscle tumors of uncertain malignant potential (STUMP) and differentiation  of these tumors on the basis of H&E staining is impossible . Th...

Aims-To study correlations between the pattern of silver stained nucleolar organiser regions (AgNORs) in chronic lymphocytic leukaemia (CLL) and parameters of tumour kinetics. To investigate whether quantitation of the AgNOR pattern can be used to discriminate between patients with stable and progressive disease.Methods-Peripheral blood smears from 48 patients with CLL, classified as having eit...

Prof. Dr. K. Metze, Department of Pathology, Faculty of Medicine, POB 6111, State University of Campinas, BR 13081 Campinas-SP (Brazil) Nucleolar organizer regions (AgNORs) have been widely studied in a variety of neoplasias, but only a few investigations deal with AgNORs in blood diseases. We therefore read with interest the study by Nakamura et al. [1] on AgNORs in acute leuke-mias, and would...

In order to assess the proliferative behaviour of ameloblastoma epithelium nine cases this neoplasm were retrieved from files Oral Pathology Service laboratory Rio Grande do Sul Federal University School Dentistry. Two proliferation marker techniques employed: AgNor - argyrophilic nucleolar organizer regions staining and cell nuclear antigen (PCNA) immunohistochemical assessment technique. Each...

BACKGROUND Apart from a number of cases of inaccurate prognosis in regard to individual patients, the inter- and intra-observer variability of the classical, histological prognosis parameters have been under repeated discussion. For this reason, a long-term analysis was carried out in regard to overall survival by means of automated microscopic image analysis of the nucleolar organizer regions ...