Cells of two teratocarcinoma stem cell lines (PCC4 azaguanine [aza] 1 and F9 5-bromodeoxyuridine [BrdU]) were fused with normal mouse spleen cells and mouse thymoma-derived cells (BW 5147), respectively. Hybrid clones were tested for the expression of molecules coded by the H-2K and -2D genes both by absorption analysis of conventional H-2 sera and by indirect antibody-binding radioimmunoassay ...

Nitrotyrosination of proteins, a hallmark of inflammation, may result in the production of MHC-restricted neoantigens that can be recognized by T cells and bypass the constraints of immunological self-tolerance. Here we biochemically and structurally assessed how nitrotyrosination of the lymphocytic choriomeningitis virus (LCMV)-associated immunodominant MHC class I-restricted epitopes gp33 and...

I. INTRODUCTION Researchers often need to generate synthetic graphs with key properties resembling those of networks of interest. This is for example the case when the full topology is unavailable or impractical to measure or use. In our work, we are interested in generating graphs that resemble online social networks in terms of their joint degree distribution (JDM) and their degree-dependent ...

In this paper, we find the values and the number of occurrences of each value of the cross-correlation function Cd(τ) when d = 2k−1 2s−1 (2 k(i+1) − 2ki + 2s+1 − 2k − 1), where n = 2k, s is an integer such that 2s divides k, and i is odd.

In order to dissect the MHC class I H-2K gene regulatory sequences, we p reviously generated transgenic mice containing various H-2K/lacZ fusion genes. However contrary to transgenes where H-2K sequences were fused to other coding sequences, none of the lacZ fusion transgenes was widely ex pressed like H-2K gene. We now show that this silencing also occurs when lacZ is inserted into a larger H-...

The purpose of this study was to determine whether or not caffeine would exacerbate renovascular hypertension. Therefore, we examined the effects of chronic caffeine administration on arterial blood pressure in rats subjected to either unilateral renal artery clipping (2K-1C rats) or sham-operation. Animals in each group were randomly assigned to receive either 0.1% caffeine in their drinking w...

Several organizations have developed prediction models for molecular breeding values (MBV) for quantitative growth and carcass traits in beef cattle using Bovine SNP50 genotypes and phenotypic or EBV data. Molecular breeding values for Angus cattle have been developed by IGENITY, Pfizer Animal Genetics, and a collaboration between researchers from Iowa State University and the University of Mis...

Let B(2k) be the set of all bicyclic graphs on 2k(k¿ 2) vertices with perfect matchings. In this paper, we discuss some properties of the connected graphs with perfect matchings, and then determine graphs with maximal index in B(2k). c © 2004 Elsevier B.V. All rights reserved. MSC: 05c50

We show that if the cardinality of a subset of the (2k − 1)-dimensional vector space over a finite field with q elements is ≫ q 2k−1− 1 2k , then it contains a positive proportional of all k-simplexes up to congruence.