Background Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are closely related diseases. PMR occurs in approximately 50 % of patients with GCA 1 ; however the prevalence subclinical has not yet been widely studied. Objectives The aim our multicenter, prospective study was to determine newly diagnosed PMR, using vascular ultrasound (US) as a diagnostic tool. Methods Eight European ce...

OBJECTIVES We sought to determine if beta-blocker therapy improves clinical outcomes of acute myocardial infarction (AMI) after successful primary percutaneous coronary intervention (PCI). BACKGROUND We have shown that pre-treatment with beta-blockers has a beneficial effect on short-term clinical outcomes in patients undergoing primary PCI for AMI. It is unknown if beta-blocker therapy after...

BACKGROUND Chikungunya virus (CHIKV) caused a major two-wave seventeen-month-long outbreak in La Réunion Island in 2005-2006. The aim of this study was to refine clinical estimates provided by a regional surveillance-system using a two-stage serological assessment as gold standard. METHODS Two serosurveys were implemented: first, a rapid survey using stored sera of pregnant women, in order to...

Pseudomonas putida KT 2442 was utilized as biocatalyst to form optoactive poly(/?-hydroxya1kanoate)s (PHAs) from a cosubstrate mixture of octanoate and the achiral polarizable carbon source 6(4-cyanophenoxy)hexanoate, CPH. COSY and heteronuclear multiplet quantum correlation experiments were used to assign ‘H and 13C NMR signals of 3-hydroxy-6(4cyanophenoxy)hexanoate (3HCPH) repeat units. The m...

Purpose: The development of colon cancer markers that can detect liver metastases early and predict which patients are at risk to develop liver metastases would have a major impact on this disease. We have previously identified G. Brunagel, et al., Cancer Research, 62: 2437–2442, 2002, nuclear matrix proteins (NMPs), which are associated with colon cancer. The objective of this study is to iden...

BACKGROUND AND PURPOSE Aspiration of secretions containing bacterial pathogens into the lower respiratory tract is the main cause of ventilator-associated pneumonia. Endotracheal tubes with subglottic secretion drainage can potentially reduce this and, therefore, the incidence of ventilator-associated pneumonia. New evidence on subglottic secretion drainage as a preventive measure for ventilato...

PURPOSE The development of colon cancer markers that can detect liver metastases early and predict which patients are at risk to develop liver metastases would have a major impact on this disease. We have previously identified G. Brunagel, et al., Cancer Research, 62:2437-2442, 2002, nuclear matrix proteins (NMPs), which are associated with colon cancer. The objective of this study is to identi...

s are listed in alphabetical order by the last name of the senior author. Identification and expression of Drosophila farnesoic acid o-methyltransferases (FaMeT): an enzyme potentially regulated by neuropeptides W.G. Bendena1, L. Dayton1 and S.S. Tobe2 1Department of Biology, Queen’s University, Kingston ON, Canada. [email protected] 2University of Toronto, Toronto Ontario, Canada. Ju...