The anesthetic effects of clove-oil-derived eugenol were studied in the zebrafish, Danio rerio (Hamilton). Acute lethality and the effects of exposures to various dosages of eugenol were measured. The estimated 96-h LC50 for eugenol was 21 ppm. Times to induction and recovery from anesthesia were measured and compared with MS-222 under similar conditions. Eugenol induced anesthesia faster and a...

Objective: The aim of this study is to compare early and follow-up outcomes late open conversions (LOC, with complete or partial endograft explantation) semi-conversions (SC, preservation) after endovascular aneurysm repair in a multicenter experience. Methods: All LOC SC performed from 1997 2020 11 vascular centers were compared. Endograft infections thrombosis excluded. Primary endpoints mort...

Two contradictory hypotheses regarding the origin of anti-human blood group A and B aggiutiuins have been advanced. According to the genetical theory proposed by Bernstein (3), Furuhata (4), Hirszfeld (5), and by others, these agglutinin~ are in* herited by linked gene pairs, each representing a blood group antigen and its complementary antibody. Thomsen (6) considers anti-?, and anti-B aggluti...

Within the United States, the national standard for radon measurements is embodied in a primary radon measurement system that has been maintained for over 50 years to accurately measure radon (222Rn) against international and national radium (226Ra) standards. In turn, all of the radon measurements made at the National Institute of Standards and Technology (NIST) and the radon transfer calibrat...

Interleukin (IL)-24, a novel tumor suppressor/cytokine exhibits antitumor activity against a broad-spectrum of human cancer cells. In a recent study, we showed that IL-24 inhibited AKT in lung cancer cells. However, the molecular mechanism of AKT inhibition by IL-24 remains elusive.The high mobility group (HMG) A1 a member of the non-histone chromosomal proteins and commonly referred to as arch...

Hemagglutination inhibition (HI) tests against whole virus (WV) influenza B/Singapore/222/79 antigen detected prevaccination serum antibody in only 15 (20%) of 50 predominantly elderly volunteers and fourfold or greater titer rises in only three (6%) after they received 1981-1982 trivalent influenza vaccine containing antigens of this virus. HI titers against ether-treated (ET) B/Singapore/222/...

It is well recognized that there is sex-dimorphic expression of mRNA and protein in the heart; however, the underlying mechanism is poorly understood. Endothelial nitric oxide synthase (eNOS) is an important regulator of cardiac function, and the expression levels of eNOS differ between male and female hearts. The aim of this study was to examine whether expression of specific microRNA (miRNA, ...

The Mexican axolotl (Ambystoma mexicanum) is an important model species in regenerative biology. Traditionally, axolotls are anesthetized using benzocaine or MS-222, both of which act to inhibit voltage gated sodium channels thereby preventing action potential propagation. In some neurophysiological experiments this is not desirable; therefore we tested propofol as an alternative anesthetic in ...

In the last few years, we have gathered experience in measurement of 222 Rn in air, water and soil-gas by absorption in polycarbonates. The method employs the remarkable absorption ability to noble gases of some polycarbonates, like Makrolon ® (the basic constructive material of CDs/DVDs). This report summarizes the key results of research and practical applications of this method. Calibration ...

BACKGROUND MicroRNAs (miRNAs) are a class of small non-coding RNAs that have recently emerged as important regulators of gene expression. They negatively regulate gene expression post-transcriptionally by translational repression and target mRNA degradation. miRNAs have been shown to play crucial roles in muscle development and in regulation of muscle cell proliferation and differentiation. M...