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BACKGROUND Osteosarcoma (OS) is a primary malignant bone tumor with high morbidity that principally emerges in children and adolescents. MiRNAs regulate a variety of normal physiologic processes and are involved in tumorigenesis and development of multiple malignancies, including OS. This study was aimed to evaluate the clinical significance of miR-130b and miR-218 in osteosarcoma patient. ME...
Cervical cancer is the third most common cancer in women worldwide. In the present study, global microRNA profiling for 79 cervical cancer patient samples led to the identification of miR-218 down-regulation in cervical cancer tissues compared to normal cervical tissues. Lower miR-218 expression was associated significantly with worse overall survival (OS), disease-free survival (DFS), and pelv...
Hepatocellular carcinoma (HCC) is the fifth most common cancer type worldwide and the third leading cause of cancer-associated mortality. To date, its pathogenesis has remained poorly understood. Previous studies have demonstrated that deregulated microRNA (miR) participates in hepatocarcinogenesis. In the present study, miR-218 and miR-520a were observed to be downregulated in human HCC cells ...
We have shown that smoking impacts bronchial airway gene expression and that heterogeneity in this response associates with smoking-related disease risk. In this study, we sought to determine whether microRNAs (miRNAs) play a role in regulating the airway gene expression response to smoking. We examined whole-genome miRNA and mRNA expression in bronchial airway epithelium from current and never...
Individuals commonly adjust joint stiffness in response to changes in environmental and task demands. The objective of the present study was to evaluate the contribution of muscular cocontraction and eccentric activity to this adjustment. In all, 30 healthy volunteers participated in the present study. The authors indirectly manipulated elbow stiffness by modifying (a) the frequency of forearm ...
To understand how land has transformed kiln in ancient Jingdezhen DongHe River Basin from the Yuan Dynasty to the Ming Dynasty, we create virtual maps of ancient study area and present such concepts that unambiguously realize a combination model. In this model, Model parameters and neighborhood rules are obtained with the cellular automata model melt Particle Swarm Optimization algorithm. Meanw...
Introduction The complex system of the cell is a network of interconnections proteins interact with other proteins or with DNA, and genes can interact functionally with one another. Cellular networks can be broken down into simpler components to facilitate their study. Three different types of analysis – modules, motifs, and network themes – that can be utilized to simplify the intricate web of...
3 Results 12 3.1 File 290, Block 8 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 3.2 File 290, Block 11 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 3.3 File 27, Block 7 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 3.4 File 218, Block 10 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 3.5 File 218, Block 12 . . . . . . . . . . . . . ...
of this Article Figures Only for this Article Reprint (PDF) Version of this Article eLetters: Submit a response to this article Similar articles found in: Radiology Online Search Medline for articles by: Ko, J. P. || Betke, M. Alert me when: new articles cite this article (Radiology. 2001;218:267-273.) © RSNA, 2001 Technical Developments Chest CT: Automated Nodule Detection and Assessment of Ch...
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