نتایج جستجو برای: 218

تعداد نتایج: 7562  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علوم بهزیستی و توانبخشی 1377

به منظور مقایسه بازی کودکان عادی و عقب مانده ذهنی تعداد 218 کودک انتخاب شدند.

2015
Yanming Li Shuge Liu Hongying Sun Yadong Yang Heyuan Qi Nan Ding Jiawen Zheng Xunong Dong Hongzhu Qu Zhaojun Zhang Xiangdong Fang Martin Pichler

microRNAs (miRNAs) are involved in a variety of biological processes. The regulatory function and potential role of miRNAs targeting the mRNA of the 5'-aminolevulinate synthase 2 (ALAS2) in erythropoiesis were investigated in order to identify miRNAs which play a role in erythroid iron metabolism and differentiation. Firstly, the role of ALAS2 in erythroid differentiation and iron metabolism in...

2017
Biao Yan Zhaoyang Hu Wenqing Yao Qiumin Le Bo Xu Xing Liu Lan Ma

MicroRNAs (miRNAs) are a class of evolutionarily conserved, 18-25 nucleotide non-coding sequences that post-transcriptionally regulate gene expression. Recent studies implicated their roles in the regulation of neuronal functions, such as learning, cognition and memory formation. Here we report that miR-218 inhibits heroin-induced behavioral plasticity. First, network propagation-based method w...

Journal: :FEMINA POLITICA – Zeitschrift für feministische Politikwissenschaft 2016

2015
Hongyu Zhao Rui Wang

BACKGROUND Accumulated studies have evaluated the association of pre-miR-218 rs11134527 polymorphism with cancer risk in Chinese population. However, the results remain controversial. METHODS To derive a more precise and more comprehensive estimation of the relationship, six studies focused on Chinese population were included for the pooled analysis for pre-miR-218 rs11134527 polymorphism usi...

2014
Yuh-Pyng Sher Li-Ju Wang Li-Ling Chuang Mong-Hsun Tsai Ting-Ting Kuo Cheng-Chung Huang Eric Y. Chuang Liang-Chuan Lai

Lung cancer is the leading cause of cancer death worldwide, and brain metastasis is a major cause of morbidity and mortality in lung cancer. CDH2 (N-cadherin, a mesenchymal marker of the epithelial-mesenchymal transition) and ADAM9 (a type I transmembrane protein) are related to lung cancer brain metastasis; however, it is unclear how they interact to mediate this metastasis. Because microRNAs ...

Journal: :The Journal of biological chemistry 2005
Alexis Nazabal Marie-Lise Maddelein Marc Bonneu Sven J Saupe Jean-Marie Schmitter

The HET-s prion protein of Podospora anserina represents a valuable model system to study the structural basis of prion propagation. In this system, prion infectivity can be generated in vitro from a recombinant protein. We have previously identified the region of the HET-s protein involved in amyloid formation and prion propagation. Herein, we show that a recombinant peptide corresponding to t...

2012
Elena Chiavacci Luca Dolfi Lorena Verduci Francesco Meghini Gaia Gestri Alberto Mercatanti Monica Evangelista Stephen W. Wilson Federico Cremisi Letizia Pitto

tbx5, a member of the T-box gene family, encodes one of the key transcription factors mediating vertebrate heart development. Tbx5 function in heart development appears to be exquisitely sensitive to gene dosage, since both haploinsufficiency and gene duplication generate the cardiac abnormalities associated with Holt-Oram syndrome (HOS), a highly penetrant autosomal dominant disease characteri...

Journal: :The Journal of the Society of Chemical Industry, Japan 1952

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید