Aflatoxins are fungal metabolites by strains of Aspergillus (A.parasiticus and A.flavus) are produced. The clinical signs of aflatoxin poisoning include surgery autopsy, histological lesions and also create effects on the production of poultry flocks in experimental and natural occurrence have been reported in broiler chickens worldwide. The main signs of aflatoxin po...

Aflatoxin B1 (AFB1) is a potent immunosuppressive agent in endotherms, which can be related to the up-regulated apoptosis of immune organs. In this study, we investigated the roles of the mitochondrial, death receptor, and endoplasmic reticulum pathways in Aflatoxin B1 induced thymocytes apoptosis. Chickens were fed an aflatoxin B1 containing diet (0.6 mg/kg AFB1) for 3 weeks. Our results showe...

Qidong City, China, has had high liver cancer incidence from endemic hepatitis B virus (HBV) infection and dietary exposure to aflatoxin. Based on etiologic studies, we began interventions in 1980 to reduce dietary aflatoxin and initiate neonatal HBV vaccination. We studied trends in liver cancer incidence rates in the 1.1 million inhabitants of Qidong and examined trends in aflatoxin exposure,...

The present investigation was an attempt to evaluate the ameliorative effect of curcumin on aflatoxin-induced changes in activities of succinate dehydrogenase (SDH) and adenosine triphosphatase (ATPase) in liver and kidney of mice. Aflatoxin was obtained by growing Aspergillus parasiticus in SMKY liquid medium. Pure curcumin (97% purity) was purchased from Hi-Media Laboratories Pvt. Ltd., Mumba...

Materials and methods: Ninety pigs (9.42 ± 0.05 kg) were used in a study with five dietary treatments: an uncontaminated control diet with no additives and four similar diets that were contaminated with 500 ng per g aflatoxin B1 (AB1) and supplemented with no additive, with 0.5% HSCAS, with an antioxidant preparation providing 125 mg per kg of ethoxyquin and 10 mg per kg of TBHQ, or with both H...

A method has been developed to determine the presence of aflatoxin B1 in the urine of animals (including humans) by utilizing commercial immunochemical kits that can be used in the field. Urine is treated with diatomaceous earth and filtered to clarify the sample; 2-3 ppb aflatoxin B1, corresponding to about 300 ppb in the ingested feed/food, can be detected in the filtered urine without furthe...

Introduction: Dracocephalum polychaetum bornum is exclusively found in a limited geographical area in the Kerman province It is used by the local people for treatment of abdominal pain, meteorism and musculoskeletal pain. No study has been performed on the effects of D. polychaetum bornum, so the aim of this work was to assess the role of the extract and essential oil of this plant on pain a...

AIM Detection of aflatoxin B1 in Livestock compound Feed and feed ingredients by high-performance thin layer chromatography (HPTLC). MATERIALS AND METHODS Chromatography was performed on HPTLC silica gel 60 F 254, aluminum sheets by CAMAG automatic TLC sampler 4, with mobile phase condition chloroform:acetone:water (28:4:0.06). Extraction of aflatoxin B1 from samples was done as per AOAC meth...

Reverse phase high pressure liquid chroma· k)graphy (HPLC) was investigated and found applicahle for determining 6 aflatoxins. Afla. toxins Mz• Mt• Gz• Gt , and Bt were completely resolved and Bz was satisfactorily separated on aCtS (10 ,urn. 4 mm id X 30 em) column with an eluting solvent of acetonitrile.water (35+ 65) and flow rate of 1.5 ml/min. Compounds were detected by ultraviolet absorba...

aflatoxins are fungal metabolites by strains of aspergillus (a.parasiticus and a.flavus) are produced. the clinical signs of aflatoxin poisoning include surgery autopsy, histological lesions and also create effects on the production of poultry flocks in experimental and natural occurrence have been reported in broiler chickens worldwide. the main signs of aflatoxin poisoning, loss of appetite, ...