Single crystals of the title compound, [Co(C(6)H(4)NO(2))(C(18)H(27)N(6)P)]NO(3), were obtained from the reaction of nitrato[tris-(2-isopropyl-imidazol-4-yl)phosphane]cobalt(II) nitrate with picolinic acid in the presence of potassium tert-butoxide as base. The coordination polyhedron around the central Co(II) ion is about halfway between square-pyramidal and trigonal-bipyramidal geometry. In t...

The ability of certain bacterial species to oxidize nicotinic acid was first reported by Allison (1) who used suspensions of bacteria isolated by Dubos and Miller (2). Koser and Baird (3) later isolated strains of Pseudomonas jluorescens which grew on a synthetic medium in which nicotinic acid was the sole carbon source. These strains did not attack isonicotinic acid, picolinic acid, or pyridin...

Kynurenines are the products of tryptophan metabolism. Among them, kynurenine and kynurenic acid are generally thought to have neuroprotective properties, while 3-hydroxykynurenine, 3-hydroxyanthranilic acid and quinolinic acid are considered neurotoxic. They participate in immunoregulation and inflammation and possess pro- or anti-excitotoxic properties, and their involvement in oxidative stre...

In Paper I (1) it was reported that the amount of the liver enzyme, picolinic carboxylase, is greatly increased in diabetic rats, while other related enzymes are not changed greatly. In this paper some of the factors that influence the level of this enzyme in rat liver are described. A major role was found for adrenal steroids, which are required for the increase to occur. The increase in enzym...

Primary leaves of 7- to 9-day-old etiolated seedlings of Phaseolus vulgaris L. var. Red Kidney infiltrated in darkness with aqueous solutions of alpha, alpha'-dipyridyl, o-phenanthroline, pyridine-2-aldoxime, pyridine-2-aldehyde, 8-hydroxyquinoline, or picolinic acid synthesize large amounts of magnesium protoporphyrin monomethyl ester and lesser amounts of magnesium protoporphyrin, protoporphy...

In order to provide technical information needed by the U.S. Nuclear Regulatory Commission to evaluate the adequacy of near-surface disposal of decontamination wastes, Brookhaven National Laboratory has measured the release of organic reagents from solidified simulated decontamination wastes. The waste streams consisted of either mixed-bed ion-exchange resins or anion exchange resins equilibrat...