Phenylacetate, a deaminated metabolite of phenylalanine, has been implicated in damage to immature brain in phenylketonuria. Because primary brain tumors are highly reminiscent of the immature central nervous system, these neoplasms should be equally vulnerable. We show here that sodium phenylacetate can induce cytostasis and reversal of malignant properties of cultured human glioblastoma cells...

The development of grape varieties with cold resistance can be an advantage for the wine industry. ‘Beimei’, interspecific hybrid variety and pleasant rose aroma, is now extensively cultivated in China. In present study, berry quality traits metabolites ‘Beimei’ other “Bei” were characterized. sugar (234 g/L–391 g/L) acid (6.2–8.3 contents four additional varieties, i.e., ‘Beihong’, ‘Beixi’, ‘B...

The present work describes the synthesis of new benzanthrone dye-3-[4-(2-phenylethyl)piperazin-1-yl]-7H-benzo[de]anthracen-7-one by bromine atom nucleophilic substitution reaction. structure obtained derivative is characterized NMR spectroscopy, mass spectrometry, and X-ray diffraction analysis. photophysical properties target compound are investigated means UV-Vis fluorescence spectroscopy in ...

The reaction of 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-pentanoic acid phenylamide with tertiary butyl carbazate and subsequent condensation of the resulting carbamate derivative with a chalcone provided a facile new approach to pyrrolo[1,2-b]pyridazine derivatives.

The title compound, [HgCl(2)(C(7)H(8)S)](n), was isolated from the reaction of MeSPh with HgCl(2). The Hg(II) atom has a distorted tetra-hedral geometry and is coordinated by one S atom and three Cl atoms. Two of the Cl atoms act as bridging ligands between the Hg atoms, forming a two-dimensional polymeric structure.