the influence of melatonin receptor 1a gene on litter size was studied in 150 ewes from zel (n=100) and naeini (n=50) sheep breeds. two restriction fragment length polymorphism (rflp) analyses were done to determine all genotypes occurring by variations at mnli and rsai restriction sites. the m and c were the most frequent alleles in both of these breeds. the mm genotype was predominant in zel ...

The purpose of this paper is to present some of the more carefully studied aspects of the preclinical toxicology of antineo-plastic agents, and apply these findings (with certain obvious cautions) to the area of environmental toxicology. Most of the studies to be described here are the result of applied toxicologic studies performed in support of the clinical introduction of new chemicals in th...

Weisi Wang, Zhiqiang Qin, Dan Zhu, Yufen Wei, Shizhu Li, Liping Duan b, # 5 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO 6 Collaborating Centre for Malaria, Schistosomiasis, and Filariasis, Key laboratory of Parasitology and Vector 7 Biology of the Chinese Ministry of Health, Shanghai, China. 8 Shanghai Key Laboratory of New Drug Design, Schoo...

isoxazole (2a-l) and cyanopyridine (3a-l) derivatives have been prepared by condensing chalcones (1a-l) with hydroxylamine hydrochloride and malononitrile respectively. while compounds 1a-l have been synthesized by the reaction of p-(3’-chloro-2’-benzo(b)thiophenoylamino)-acetophenone with different aldehydes. all the compounds were screened for their antitubercular and antimicrobial activities...