نتایج جستجو برای: 17 alpha hydroxyprogesterone caproate

تعداد نتایج: 467684  

2015
Lorena M. Amaral

Preeclampsia (PE) is a complex disorder, occurring during the third trimester of gestation characterized by hypertension with proteinuria, increased uterine artery resistance (UARI), elevated inflammatory cytokines and endothelial dysfunction during pregnancy. 17-hydroxyprogesterone caproate (17-OHPC), a synthetic hormone called progestogen or progestin, is already approved by US Food and Drug ...

Journal: :General and comparative endocrinology 2002
Enrique M Rodríguez Laura S López Greco Daniel A Medesani Hans Laufer Milton Fingerman

The effect of methyl farnesoate (MF) on the ovaries of female red swamp crayfish, Procambarus clarkii, undergoing vitellogenesis was determined both in vivo and in vitro. The in vivo assay showed a positive effect of MF on oocyte growth when injected alone and in combination with 17 beta-estradiol, but not in combination with JHIII or 17 alpha-hydroxyprogesterone. A higher level of incorporatio...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2008
Shringi Sharma Junhai Ou Stephen Strom Don Mattison Steve Caritis Raman Venkataramanan

Preterm delivery, that is delivery before 37 completed weeks of gestation, is the major determinant of neonatal morbidity and mortality. Until recently, no effective therapies for prevention of preterm birth existed. In a recent multicentered trial, 17alpha-hydroxyprogesterone caproate (17-OHPC) reduced the rate of preterm birth by 33% in a group of high-risk women. Limited pharmacologic data e...

Journal: :The Biochemical journal 1986
S B Mahato S Banerjee

Fermentation of 17-hydroxyprogesterone with a Bacillus species (IICB-301) in a modified nutrient medium under aerobic conditions yielded androst-4-ene-3,17-dione and 15 alpha,17-dihydroxypregn-4-ene-3,20-dione in addition to a new pregnane analogue, 6 beta,17,20 alpha-trihydroxypregn-4-ene-3-one. Each microbial metabolite was characterized by the application of various spectroscopic techniques....

Journal: :Obstetrics and gynecology 2013
Lisa M Bodnar Dwight J Rouse Valerija Momirova Alan M Peaceman Anthony Sciscione Catherine Y Spong Michael W Varner Fergal D Malone Jay D Iams Brian M Mercer John M Thorp Yoram Sorokin Marshall W Carpenter Julie Lo Susan M Ramin Margaret Harper

OBJECTIVE To assess whether there was an independent association between maternal 25-hydroxyvitamin D concentrations at 24-28 weeks of gestation and preterm birth in a multicenter U.S. cohort of twin pregnancies. METHODS Serum samples from women who participated in a clinical trial of 17 α-hydroxyprogesterone caproate for the prevention of preterm birth in twin gestations (2004-2006) were ass...

2015
Afsar Sadat Tabatabaei Bafghi Elham Bahrami Leila Sekhavat

BACKGROUND Preterm birth is a worldwide health concern due to its various negative consequences. Therefore, the prevention of preterm birth is a top priority for healthcare systems in all countries. OBJECTIVE To compare the effectiveness of vaginal versus intramuscular progesterone in the prevention of preterm delivery. METHODS This randomized clinical trial was conducted at Shahid Sadoughi...

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