The number of diabetic patients is increasing every year, and new model animals are required to study the diverse aspects of this disease. An experimental obese animal model has reportedly been obtained by injecting monosodium glutamate (MSG) to a mouse. We found that ICR-MSG mice on which the same method was used developed glycosuria. Both female and male mice were observed to be obese but had...

Background and Aims: Metabolic syndrome (MetS) with modifiable non-modifiable risk factors is an increasing global concern. It predisposes individuals to a significant cardiovascular that the leading cause of death in Iran. We investigated MetS prevalence its Shiraz, Methods: 7225 participants age range 40 70 years were recruited from Shiraz Heart Cohort Study. was diagnosed according Adult Tre...

The main purpose of this study was to examine the relative contribution of respiratory mechanical factors and the increased metabolic cost of locomotion to exertional breathlessness in obese women. We examined the relationship of intensity of breathlessness to ventilation (VE) when exertional oxygen uptake (VO2) of obesity was minimized by cycle exercise. Eighteen middle-aged (54+/-8 yr, mean+/...

OBJECTIVES The aim of this study was to evaluate the association between Fasting Blood Glucose (FBG) level and Waist Circumference (WC) in men and women among 25-65 years old people in the north of Iran. MATERIAL AND METHODS This was a cross-sectional and analytical research gender that carried out on the 1797 subjects (941 males and 856 females) between 25-65 years old using multistage clust...

This study was done to elucidate the relationship between postprandial leptin and obesity, and the possible influence of the circadian rhythm on the dynamic leptin response to an oral fat load (OFLT). In experiment 1, we measured the leptin and insulin responses to an oral fat load in 16 non-diabetic obese subjects and in 16 healthy controls, matched for age and gender. In experiment 2, we meas...

Abstract Background and Aims The pathogenesis of obesity related-renal disease is unknown. Gender differences may have a role in renal damage obesity. In particular, menopause can promote obese women. previous study we observed that male female mice developed albuminuria, hyperfiltration glomerulomegaly, these changes were more severe those ovariectomized females. this evaluated inflammation li...

BACKGROUND Neck circumference (NC), is an emerging marker of obesity and associated disease risk, but is challenging to use as a screening tool in children, as age and sex standardized cutoffs have not been determined. A population-based sample of NC in Canadian children was collected, and age- and sex-specific reference curves for NC were developed. METHODS NC, waist circumference (WC), weig...

OBJECTIVE To examine links between obstructive sleep apnea (OSA), insulin resistance, and dyslipidemia. STUDY DESIGN Obese (body mass index [BMI] >95th percentile for age and gender) children who snored (n = 62, 46 males, age 10.89 [5-16 years] underwent polysomnography and metabolic studies. RESULTS Respiratory disturbance index (RDI) was 9.23 (0-95), with 23 children (39%) recommended for...

As body mass index (BMI) and waist hip ratio (WHR) are indices of obesity and as obesity is known to reduce flow rates, an attempt had been made to correlate these indices with peak expiratory flow rate (PEFR) and see whether there is any gender difference in this. 40 males and 40 females in the age group of 18 to 22 years participated in this study in which 20 were obese and another 20 were no...