This study aimed to investigate tourniquet-induced compartment syndrome of the limb, consequential development multiple organ dysfunction syndrome, and its counteraction with pentadecapeptide BPC 157 therapy.

This essay looks at the historic significance of an APS classic paper (http://www.the-aps.org/publications/classics/) that is freely available online: Falk G. Maturation of renal function in infant rats. Am J Physiol 181: 157-170, 1955 (http://ajplegacy.physiology.org/cgi/reprint/181/1/157).