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MicroRNAs (miRNAs) represent a class of small non-coding RNAs regulating gene expression by inducing RNA degradation or interfering with translation. Aberrant miRNA expression has been described for several human malignancies. Herein, we show that miR-145 is down-regulated in human cancer cell line MCF-7 when compared to normal human mammary epithelial cell line MCF10A. Overexpression of miR-14...
10.2 Physics Principles of In-line X-ray Phase-contrast Imaging......................................145 10.2.1 Attenuation, Phase Shift, and Optical Transmission ...................................145 10.2.2 System Configuration of In-line Phase-contrast Imaging............................145 10.2.3 Theoretical Framework of In-line Phase-contrast Imaging with Ideal Imaging Systems ...............
MicroRNAs are important regulators of gene expression and have been suggested to play a key role in tumorigenesis. In this study, we show that miR-145 is significantly downregulated in glioma cell lines compared to normal brain tissue and negatively regulates tumorigenesis. Restoration of miR-145 in glioma cells significantly reduced in vitro prol...
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