The solution methods based on semidefinite programming (SDP) relaxations for sensor network localization (SNL) problems can not handle very large-sized SNL problems. We present a continuation method using the gradient descent method to efficiently solve large-sized SNL problems. We first formulate the problem as an unconstrained optimization problem and then apply the continuation on the distan...

Heterogeneous supercomputers with combined general-purpose and accelerated CPUs promise to be the future major architecture due to their wide-ranging generality and superior performance / power ratio. However, developing applications that achieve effective scalability is still very difficult, and in fact unproven on large-scale machines in such combined setting. We show that an effective method...

Many lines of evidence suggest that oxidative stress is important in the pathogenesis of Alzheimer disease. In particular, beta-amyloid, which is found abundantly in the brains of Alzheimer disease patients, is toxic in neuronal cell cultures through a mechanism involving free radicals. Vitamin E prevents the oxidative damage induced by beta-amyloid in cell culture and delays memory deficits in...

OBJECTIVE To evaluate activities of a nurse led minor injuries unit based in a community hospital situated eight miles away from its sister district hospital in Crawley to demonstrate whether nurses can provide an alternative service. DESIGN "Walk in" service provided by emergency nurse practitioners (ENPs) working within protocols and parameters with supervision from the accident and emergen...

Cell-based therapies have the potential to make a large contribution toward currently unmet patient need and thus effective manufacture of these products is essential. Many challenges must be overcome before this can become a reality and a better definition of the manufacturing requirements for cell-based products must be obtained. The aim of this study is to inform industry and academia of cur...