It is characteristic of collaborative engineering design that precedence relationships among design activities contain information flow conflicts. Due to multi-actors interaction, conflicts can emerge from disagreements between designers about proposed designs. Hence, a critical element of collaborative design is tomanage the detected conflicts and particularly the impacts once they are resolve...

A key challenge in quantitative ChIP-seq is the normalisation of data in the presence of genome-wide changes in occupancy. Analysis-based normalisation methods were developed for transcriptomic data and these are dependent on the underlying assumption that total transcription does not change between conditions. For genome-wide changes in transcription factor binding, these assumptions do not ho...

We review the thermal characteristics of all-metallic sandwich structures with two dimensional prismatic and truss cores. Results are presented based on measurements in conjunction with analytical modeling and numerical simulation. The periodic nature of these core structures allows derivation of the macroscopic quantities of interest—namely, the overall Nusselt number and friction factor—by me...

1 Solid tumors of childhood display specific serum microRNA profiles Matthew J. Murray, Katie L. Raby, Harpreet K. Saini, Shivani Bailey, Sophie V. Wool, Jane M. Tunnacliffe, Anton J. Enright, James C. Nicholson, Nicholas Coleman. 1 Department of Paediatric Haematology and Oncology, Addenbrooke’s Hospital, Hills Road, Cambridge, CB2 0QQ, UK 2 Department of Pathology, University of Cambridge, Te...

This paper presents theoretical modelling of the sound transmission loss through double-leaf lightweight partitions stiffened with periodically placed studs. First, by assuming that the effect of the studs can be replaced with elastic springs uniformly distributed between the sheathing panels, a simple smeared model is established. Second, periodic structure theory is used to develop a more acc...

BACKGROUND We investigated whether right ventricular dysfunction (RVD) as assessed by echocardiogram can be used as a prognostic factor in hemodynamically stable patients with acute pulmonary embolism (PE). Short-term mortality has been investigated only in small studies and the results have been controversial. METHODS A PubMed search was conducted using two keywords, "pulmonary embolism" and...