We have studied the possible interactions between the mismatch repair system and p53 in a human colon cancer cell line, HCT-116 (known to have a homozygous mutation in mismatch repair gene hMLH1 on chromosome 3) and in a clone obtained after insertion of a single copy of chromosome 3 (HCT-116+ ch3). Loss of DNA mismatch repair activity resulted in resistance to cisplatin (DDP). p53 accumulated ...

Abstract Introduction Liver resection is a most effective treatment for patients with operable primary or secondary cancer deposits. The role of trainee as lead surgeon versus consultant performing liver resections and its impact on surgical outcomes had never been reported. Methods Materials This study was aimed to assess the including operative time, acute kidney injury (AKI), bile leak, seps...

AMA Tkaczyk F. A model of nursing care for a patient after percutaneous closure an atrial septal defect. Nursing Problems / Problemy Pielęgniarstwa. 2022;30(4):111-116. doi:10.5114/ppiel.2022.126819. APA Tkaczyk, (2022). Pielęgniarstwa, 30(4), 111-116. https://doi.org/10.5114/ppiel.2022.126819 Chicago Filip Miłosz. 2022. "A defect". Pielęgniarstwa 30 (4): Harvard pp.111-116. MLA defect." vol. 3...