Background One of the hallmarks Alzheimer’s disease (AD), an age-related progressive form dementia, is accumulation amyloid beta (Aβ42) plaque, which manifests in decline cognitive function. The these Aβ42 plaques trigger hyperphosphorylation tau, a microtubule associated protein, results intracellular neurofibrillary tangles (NFTs) due to destabilization microtubules. Method We employed Gal4/U...

PURPOSE To investigate the prevalence of scleral hyaline plaque among older adults in the city of Niterói in southeastern Brazil. A second goal was to assess the correlation between scleral hyaline plaque and several age-related diseases, including eye diseases and systemic diseases. METHODS The study sample comprised 667 participants who were followed for 15 months. The study had a prospecti...

Sclerochoroidal calcification (SCC) is a frequent masquerader of choroidal melanoma with important systemic associations such as hyperparathyroidism and parathyroid adenoma. Herein, we describe a case of a 67-year-old male who presented with an amelanotic choroidal lesion in the right eye (OD) and a history of kidney stones. Ultrasonography showed the lesion to be flat and calcified OD. Inciden...

The concept of whole retina radiotherapy for infants and youngsters with retinoblastoma is not new. Such treatment was pioneered in the early 1960's shortly after the linear accelerator became available for medical use (Bagshaw & Kaplan, 1966). The linear accelerator provided the possibility of using focused small field megavoltage radiation beams to treat the entire retina while simultaneously...

in the present study, variation among different bacterial strains was observed in the plaques of tobacco chewers (tc) as compared to those from normal persons (non tobacco chewers) (ntc). bacterial strain j1 (dominant in the plaques of ntc) did not initiate the process of adhesion (biofilm formation) until it appeared to have reached a required population density necessary for the production of...

introduction: until now, many models have been presented for optical study of the human eye. in recent years, surgery on the anterior section of the eye (such as cataract and photo-refractive surgery) has increased, so a study on the optics of the eye and evaluation of vision quality has become more important. material and methods: in this article, some of these models are considered. they incl...

IMPORTANCE Patients with larger choroidal melanomas are being treated with plaque radiation therapy. OBJECTIVE To report the methods and results of palladium-103 brachytherapy for American Joint Committee on Cancer, 7th edition, T3- and T4-sized choroidal melanomas. DESIGN, SETTING, AND PARTICIPANTS A retrospective analysis of the results of a clinical case series over a 10-year period of 4...