Cultures of the blue-green alga, Aphanocapsa, were grown under iron-limiting conditions and changes in concentration of redox components of the photosynthetic electron transport chain, particularly iron-sulfur centers, were monitored by spectroscopic methods. A moderate iron depletion (1/10 of the normal concentration) had little effect on photosynthetic electron transport reactions and growth....

The endeavours of physicians taxed with the problem of iron deficiency over the last 100 years have successfully eliminated this as an issue of hematological interest. Iron overload, although by no means a new problem, has drawn much more attention over the last few decades. The development of reliable indicative tests of iron status since the early 1970s has sparked a revolution in our underst...

Heart failure is the leading cause of mortality in patients with transfusional iron (Fe) overload in which myocardial iron uptake ensues via a transferrin-independent process. We examined the ability of L-type Ca channel modifiers to alter Fe uptake by isolated rat hearts and ventricular myocytes. Perfusion of rat hearts with 100 nmol/L Fe and 5 mmol/L ascorbate resulted in specific Fe uptake o...

zinc and iron nano-oxides (100 ppb) were promoted the hypericin and hyperforin production in hypericum perforatum cell suspension culture. high performance liquid chromatography method was used for detectection and identification of hypericin and hyperforin in h. perfuratum cell suspension cultures elicited with different concentrations of zinc and iron nano-oxide (0, 50, 100 and 150 ppb) after...

BACKGROUND The ideal screening test would be capable of identifying iron deficiency in the absence of anemia. We tried to detect role of urinary hepcidin-25 level in early prediction of iron deficiency in children. METHODS This is a case control study performed on 100 children in Hematology Unit of Pediatric Department, Zagazig University Hospital, Egypt. Our study included 25 cases of iron d...

OBJECTIVES To compare the safety and efficacy of iron carboxymaltose with ferrous sulfate to treat iron deficiency anemia in the post partum. METHODS Patients were randomized (2:1 ratio) to receive iron carboxymaltose (up to 3 weekly doses of 1000 mg maximum, applied in 15 min; n=227) or ferrous sulfate (100 mg twice daily, 12 weeks; n=117). Changes in hemoglobin and iron stores up to week 12...

had no relevance to his illness. He was a non-pigmented normotensive man with an enlarged (6 cm below costal margin) firm non-tender liver, and was otherwise normal. Apart from minor abnormality of liver function tests the results of other relevant laboratory investigations were normal. The serum iron was 57 7 Mmol/l (322 Mg/100 ml) and 100 saturated transferrin. The resting electrocardiogram (...

BACKGROUND Anemia management protocols in hemodialysis (HD) units differ conspicuously regarding optimal intravenous (IV) iron dosing; consequently, patients receive markedly different cumulative exposures to IV iron and erythropoiesis-stimulating agents (ESAs). Complementary to IV iron safety studies, our goal was to gain insight into optimal IV iron dosing by estimating the effects of IV iron...

Heart failure is the leading cause of mortality in patients with transfusional iron (Fe) overload in which myocardial iron uptake ensues via a transferrin-independent process. We examined the ability of L-type Ca2+ channel modifiers to alter Fe2+ uptake by isolated rat hearts and ventricular myocytes. Perfusion of rat hearts with 100 nmol/L 59Fe2+ and 5 mmol/L ascorbate resulted in specific 59F...