Open Source Software kann ohne Zahlung von Lizenzgebühren eingesetzt werden. Jedoch zwingen Lizenzen, die – wie die General Public License (GPL) auf dem „Copyleft“-Prinzip beruhen, den Entwickler dazu, Veränderungen an dieser Software wiederum mit Quellcode freizugeben. Dieser Beitrag analysiert, welche Möglichkeiten aus rechtlicher Sicht bestehen, Open Source Software im Rahmen von proprietäre...

A major phenotypic trait of the Mycobacterium avium complex is the ability to produce rough and smooth colony variants. The chemical basis of this morphological variation is the loss of an antigenic surface structure, termed glycopeptidolipid (GPL), by rough variants. Using M. avium serovar 2 strain 2151 as a model system, this laboratory previously reported that rough variants arise via the de...

A major challenge in preventing preterm birth (PTB) is identifying women at greatest risk. This pilot study prospectively examined the differences in vaginal microbiota and metabolite profiles of women who delivered prematurely compared to their term counterparts in a cohort of asymptomatic (studied at 20-22, n = 80; and 26-28 weeks, n = 41) and symptomatic women (studied at 24-36 weeks, n = 37...

The aim of the present study was to examine lipid profile, fractions and peroxidation state in blood neutered cats with obesity diabetes. Three groups (males females) were formed for study. We compared (7-9 points on a 9-point BCS scale), complicated by diabetes, clinically healthy animals normal body condition scores (4-5 points). Lipidogram parameters, high-density lipoprotein (HDL), low-dens...

Mycobacterial glycopeptidolipid (GPL) interactions with membranes were analysed with monolayer experiment, using GPLs bearing 3, 1, or 0 carbohydrate residues (GPL3, GPL1, GPL0). Compression isotherms and surface potential determinations suggested that the glycopeptidic moiety of GPL3 permanently dipped in water, while those of GPL1 and GPL0 can lay in the interface. Insertion of GPL molecules ...

BACKGROUND Although the incidence of pulmonary tuberculosis is decreasing, the number of immunocompetent patients with Mycobacterium avium complex (MAC) pulmonary disease is steadily increasing. Therefore, albeit not contagious, MAC pulmonary disease needs to be diagnosed rapidly and accurately. We examined the serodiagnostic contributions of serum immunoglobulin G antibody titers against the s...

It is difficult to distinguish pulmonary disease due to Mycobacterium avium complex (MAC) from that due to other mycobacteria, such as Mycobacterium tuberculosis and Mycobacterium kansasii. We developed an enzyme immunoassay (EIA) for diagnosis of MAC pulmonary diseases that uses glycopeptidolipid (GPL) antigens specific for MAC, and we used it for diagnosis in immunocompetent patients. The mea...

BACKGROUND It is well known that gastric mucosa dysplasia and intestinal metaplasia are gastric precancerous lesions (GPL). Moxibustion treatment of Liangmen (ST21) and Zusanli (ST36) alleviated the inflammatory response and dysplasia of gastric mucosa in our previous study. The purpose of this study was to further examine the underlying mechanism of moxibustion treatment of ST21 and ST36 on GP...

3 Departamento de Gen4tica y Microbiologla, Universidad de Murcia, Facuitad de Medicina, Universidad de Murcia, Campus Universitario de Espinardo, Aptdo 4021, 30100 Murcia, Spain Fatty and mycolic acids and the pattern of glycolipids were studied in a collection of 34 strains of 'Mycobacterium habana' and in two strains of Mycobacterium simiae. Major glycolipids of these micro-organisms were as...