When the horseradish peroxidase reaction is stopped with acid, the decay of unconverted hydrogen peroxide is responsible for the further oxidation of o-phenylenediamine. This leads to a time-dependent flattening of the standard curve in the enzyme immunoassay, after the reaction has been stopped. Addition of reducing agents, such as sulphite ions, to the stopping solution, prevents the further ...

In this paper, a synthesis and characterization of novel three coordinate 2-{9-(10-Bromoanthracenyl)}-1,3-dihydro-1H-[d]-1,3,2-benzodiazaborole from cyclo-condensation reaction o-phenylenediamine 10-bromoanthracene-9-boronic acid is described. The desired product was obtained in 0.343 g (92% yields) with its structure characterized by 1H, 11B, 13C NMR, HRMS FT-IR.

A three-component reaction between 1,2-phenylenediamine, ferrocenecarbaldehyde, and isocyanides in the presence of a catalytic amount of p-toluenesulfonic acid for the synthesis of 3,4-dihydroquinoxalin-2-amine derivatives containing a ferrocene unit is reported. This approach is an effective procedure because the products have a broad spectrum of biological and pharmacological activities such ...

In an attempt to synthesize a 2-substituted benzimidazole from the reaction of o-phenylenediamine and isophthalic acid in the presence of acetone and ethanol under microwave irradiation, a salt of the isophthalate ion and 2,2,4-trimethyl-2,3-dihydro-1H-1,5-benzodiazepin-5-ium ion was obtained. The condensation of two moles of acetone with the amine groups resulted in the formation of the benzod...

both as crystals and in solution.1–3 There are rare examples of trans amide of N-methyl aromatic anilide in crystals, though the introduction of methyl group(s) ortho to the amide bond reduces the ratio of the cis-amide form of N-methylbenzanilides in solution.3 In this paper, we report on the crystal structure of 1,2-bis(N-2-fluorobenzoyl-N-methylamino)benzene (1, Fig. 1), which has two trans-...

In order to study the proclivity of primary amine groups act as halogen bond acceptors, three aromatic diamines (p-phenylenediamine (pphda), benzidine (bnzd) and o-tolidine (otol)) were cocrystallised with perfluorinated iodobenzenes (1,4-tetrafluorodiiodobenzene (14tfib), 1,3-tetrafluorodiiodobenzene (13tfib) 1,3,5-trifluorotriiodobenzene (135tfib)) donors. Five cocrystals obtained: (pphda)(14...

There is an association between occupational exposure to hair dyes and incidence of cancers. Permanent oxidant hair dyes are consisted of many chemical components including ortho-phenylenediamines. To clarify the mechanism of carcinogenesis by hair dyes, we examined DNA damage induced by mutagenic ortho-phenylenediamine (o-PD) and its derivatives, 4-chloro-ortho-phenylenediamine (Cl-PD) and 4-n...

The DPD (N, N-diethyl-p-phenylenediamine) is introduced in the present study as an analytical reagent for direct, rapid, easy, and sensitive spectrophotometric detection of hexavalent chromium Cr (VI) species which health hazard. oxidization colorless with results a red color radical (DPD•+) at pH 4.39. intensity directly proportional to concentration. By utilizing UV-Vis spectrophotometer, mea...

We present results on a new fullerene-based anchoring group for molecular electronics. Using lithographic mechanically controllable break junctions in vacuum we have determined the conductance and stability of single-molecule junctions of 1,4-bis(fullero[c]pyrrolidin-1-yl)benzene. The compound can be self-assembled from solution and has a low-bias conductance of 3 x 10(-4) G0. Compared to 1,4-b...