Deciphering the mode of action (MOA) of new antibiotics discovered through phenotypic screening is of increasing importance. Metabolomics offers a potentially rapid and cost-effective means of identifying modes of action of drugs whose effects are mediated through changes in metabolism. Metabolomics techniques also collect data on off-target effects and drug modifications. Here, we present data...

We sought to determine the role of human papillomavirus (HPV) E6 and E7 oncogenes in nuclear beta-catenin accumulation, a hallmark of activated canonical Wnt signaling pathway. We used HPV16-positive oropharyngeal cancer cell lines 147T and 090, HPV-negative cell line 040T, and cervical cell lines SiHa (bearing integrated HPV16) and HeLa (bearing integrated HPV18) to measure the cytoplasmic and...

Atopic dermatitis (AD) is a well-studied chronic inflammatory skin disease. However, analysis of the disease’s impact on serum proteome has not been well investigated. With this study we aimed for comprehensive characterization disease and its change after systemic treatment. Global spectrometric profiles have generated from 61 AD patients before (BL) 3 months initiation dupilumab treatment (DP...

Background documents: N1944 Encoding Egyptian Hieroglyphs in Plane 1 of the UCS. Michael Everson. 1999-01-09. L2/15-123 Proposal to encode three control characters for Egyptian Hieroglyphs (revised). Bob Richmond. 2015-05-04. L2/16-018 Proposal to encode three control characters for Egyptian Hieroglyphs (revised). Bob Richmond, Andrew Glass. 2016-01-27. L2/16-090 Comments on three control chara...

s 59 Advanced X-Ray and CT Techniques 60 Image Analysis, Bioinformatics, Computational Modeling 68 Magnetic Resonance Research 88 Molecular Imaging 124 Publications and Presentations 147 Peer-Reviewed Presentations at Scientific Meetings 148 Other Scientific Meeting Presentations 157 Published Papers 164 Books & Book Chapters 181 Papers Submitted or In Press 184 Funded Research Projects 195 NIH...