Identification of protein families is a computational biology challenge that needs efficient and reliable methods. Here we introduce the concept of dominance and propose a novel combined approach based on Distance Alignment Search Tool (DAST), which contains an exact algorithm with bounds. Our experiments show that this method successfully finds the most similar proteins in a set without solvin...

BACKGROUND Management trends in early chronic kidney disease (CKD) and their associations with clinical outcomes have not previously been reported. METHODS We evaluated incident (Stage G3A) CKD patients from an integrated health care system in 2004-06, 2007-09 and 2010-12 to determine adjusted trends in screening (urinary protein quantification), treatment [prescription for angiotensin-conver...

Performance test records from on-farm tests of young Polish Large White boars and reproductive records of Polish Large White sows from 94 nucleus farms during 1978 to 1987 were used to estimate population parameters for the measured traits. The number of boar performance records after editing was 114,347 from 3,932 sires, 21,543 dams, 44,493 litters and 1,075 herd-year-seasons. Reproductive per...

BACKGROUND Increasingly complex structural/congenital cardiac interventions require efforts at reducing patient/staff radiation exposure. Standard follow-up protocols are often inadequate in detecting all patients that may have sustained radiation burns. METHODS Single-center retrospective chart review divided into four intervals. Phase 1 (07/07-06/08, 413 procedures (proc)): follow-up based ...

UNLABELLED Aims/Introduction:  Fulminant type 1 diabetes is a subtype of type 1 diabetes characterized by a remarkably abrupt onset of insulin-deficient hyperglycemia within a few days. The aim of the present study was to clarify characteristic class II HLA genotypes in a large number of patients with fulminant type 1 diabetes to date. MATERIALS AND METHODS   We analyzed the HLA-DRB1 and DQB1...

The Auroral Electrojet (AE) indices, which are composed of four indices (AU, AL, AE, and AO), are calculated from the geomagnetic field data obtained at 12 geomagnetic observatories that are located in geomagnetic latitude (GMLAT) of 61.7–70. The indices have been widely used to study magnetic activity in the auroral zone. In the present study, we examine magnetic local time (MLT) dependence of...

*Corresponding author (email: ) Imperial College London Wellcome Trust Centre for Clinical Tropical Medicine (LC) and Laboratorio de Investigación de Enfermedades Infecciosas (DAJM), Universidad Peruana Cayetano Heredia, Av. Honorio Delgado No 430, Urb. Ingeniería, Perú Received : 09-11-06 Accepted : 21-11-06 The urgent need for improved diagnostic tools for detection of t...

The results of a molecular beam microwave Fourier transform study of 1,2,3-trifluorobenzene and its monosubstituted 1 'C-isotopomers, all observed in natural abundance, are presented. Typically 30 transitions were observed for each isotopomer. Centrifugal perturbation theory up to fourth order was used to analyse the observed rotational spectra. Due to the high sensitivity and resolution of the...

1 Internal Medicine, Resident in Gastroenterology at the Universidad Militar Nueva Granada, Hospital Militar Central. Bogotá, Colombia. 2 Internal Medicine, Gastroenterologist, Chief of the Department of Gastroenterology at Hospital Militar Central, Professor of Medicine at the Universidad Militar Nueva Granada. Bogotá, Colombia. 3 Internal Medicine, Gastroenterologist, Professor of Medicine at...