نتایج جستجو برای: 052 and 120
تعداد نتایج: 16839129 فیلتر نتایج به سال:
BACKGROUND The HIV Prevention Trials Network (HPTN) 052 trial demonstrated that early initiation of antiretroviral therapy (ART) reduces human immunodeficiency virus (HIV) transmission from HIV-infected adults (index participants) to their HIV-uninfected sexual partners. We analyzed HIV from 38 index-partner pairs and 80 unrelated index participants (controls) to assess the linkage of seroconve...
Fitness landscapes underlie the dynamics of evolutionary processes and are a key concept of evolutionary theory. Recent research on molecular folding and on evolutionary algorithms has demonstrated that such landscapes are also important for understanding problems of chemistry and of combinatorial optimization. In these cases free energy or cost functions are used instead of biological fitness ...
The aim of this review is to summarise the evidence on the population-level effect of antiretroviral therapy (ART) in preventing HIV infections, and to discuss potential implications in the European context of recommending starting ART when the CD4 count is above 350 cells/mm3. The ability of ART to reduce the risk of HIV transmission has been reported in observational studies and in a randomis...
This paper describes a new determination of the primordial helium abundance (YP ), based on the abundance analysis of five metal-poor extragalactic H ii regions. For three regions of the sample (SBS 0335–052, I Zw 18, and H 29) we present tailored photoionization models based on improved calculations with respect to previous models. In particular, we use the photoionization models to study quan...
Abundance observations indicate the presence of rapid-neutron capture (i.e., r-process) elements in old Galactic halo and globular cluster stars. Recent observations of the r-process-enriched star BD+17◦3248 include new abundance determinations for the neutron-capture elements Cd I (Z=48), Lu II (Z = 71) and Os II (Z = 76), the first detections of these elements in metal-poor r-process-enriched...
Objective: We evaluated whether nutritional status and long-term prognosis of patients with refractory hepatic ascites improved after treatment with tolvaptan. Methods: We retrospectively studied data for a total of 50 patients with hepatic ascites treated with tolvaptan from April 2011 to January 2016. Bloatedness was assessed by using the Japanese version of the support team assessment schedu...
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