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We report Very Large Telescope observations of 11 lensed quasars, designed to measure the redshifts of their lens galaxies. We successfully determined the redshifts for seven systems, five of which were previously unknown. The securely measured redshifts for the lensing galaxies are: HE0047−1756 z = 0.408; PMNJ0134−0931 z = 0.766; HE0230−2130 z = 0.522; HE0435−1223 z = 0.455; SDSS0924+021 z = 0...
نارساییهای کارکرد اجرایی کودکان با اختلال یادگیری خاص میتواند دریچهای جدیدی را جهت درمان و علت شناسی در این کودکان باز کند. تخریب کارکرد اجرایی یکی از چندین فنوتیپهای شناختی بالقوه در اختلال یادگیری خاص است. بنابراین هدف این مطالعه مقایسه کارکردهای اجرایی دانشآموزان با اختلال یادگیری خاص و دانشآموزان عادی است. در این پژوهش مقطعی 29 دانشآموز مبتلا به اختلال یادگیری خاص (نارسایی خواندن) و ...
*Corresponding author: Azamat Sabouri Arteh. Cardiovascular Research Center, Department of Cardiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran E-mail: [email protected] Tel:051-38593032 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons. org/licenses/by/3.0), which permits unrestri...
Crystallization and preliminary X-ray diffraction analysis of Trap1 complexed with Hsp90 inhibitors.
Hsp90 is a molecular chaperone responsible for the assembly and regulation of many cellular client proteins. In particular, Trap1, a mitochondrial Hsp90 homologue, plays a pivotal role in maintaining mitochondrial integrity, protecting against apoptosis in cancer cells. The N (N-terminal)-M (middle) domain of human Trap1 was crystallized in complex with Hsp90 inhibitors (PU-H71 and BIIB-021) by...
Introduction Cryopyrin-associated periodic syndromes (CAPS) are a group of dominantly inherited disorders caused by gainof-function NLRP3 mutations. These disorders represent different degrees of severity of a same disease being familial cold autoinflammatory syndrome the milder form, Muckle-Wells syndrome an intermediate form and chronic infantile neurologic cutaneous and articular syndrome th...
Introduction Familial Mediterranean fever (FMF) is an autoinflammatory disorder characterized by recurrent, inflammatory, self-limited episodes of fever and serositis. Neutrophils are one of the key players in the pathophysiology of FMF. Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine involved in several inflammatory processes including innate and adaptive immune response...
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