Based on a general theory of detonation waves with an embedded sonic locus that we have previously developed, we carry out asymptotic analysis of weakly curved slowly varying detonation waves and show that the theory predicts the phenomenon of detonation ignition and failure. The analysis is not restricted to near ChapmanJouguet detonation speeds and is capable of predicting quasi-steady, norma...

ABSTRACT Previous studies mostly measured sharia financial inclusion using an index consisting of three dimensions: accessibility, availability, and usage. This research develops it by adding a digitalization dimension so that there are 4 dimensions in measuring Indonesia index. The first objective this study is to visually illustrate the results calculating (in map form) 33 provinces Indonesia...

Objective: To establish the normal electrophysiological data for the median, ulnar and radial nerves and to compare our results with the Western data published in the literature. Methods: Nerve conduction studies were performed prospectively in the upper limbs of 50 carefully screened healthy individuals between the ages of 16 and 56 years using standardized technique. Results: The median motor...

We recently performed an updated network meta-analysis (NMA) to inform the British Association of Dermatologists guidelines for biologic therapy psoriasis (Smith et al., 2020Smith C.H. Yiu Z.Z. Bale T. Burden A.D. Coates L.C. Edwards W. al.British 2020 – a rapid update [e-pub ahead print].Br J Dermatol. 2020; 183: 628-637Crossref PubMed Scopus (39) Google Scholar). During this process, we ident...

==================== Dr. Ing-Shouh Hwang (Institute of Physics, Academia Sinica; E-mail: [email protected]) Talk Title: Imaging of Soft Matters in Water with Atomic Force Microscopy Abstract: Operation of atomic force microscopy (AFM) in aqueous environment is of great importance. Only this environment allows us to image and probe biological samples in their physiological conditions, t...

In this study, we have characterized the signaling pathways mediated by CXCR4 in breast cancer cells and its role in breast cancer cell invasion and migration. Stromal cell-derived factor 1A (SDF-1A; CXCL12) stimulation of breast cancer cells resulted in phosphoinositide 3-kinase (PI-3K) activation, AKT phosphorylation, and activation of the FKHRL1 transcription factor. In addition, SDF-1A indu...

BackgroundAberrations in the coagulation system have been implicated pathogenesis of interstitial lung disease (ILD). Anticoagulants proposed as a potential therapy ILD; however, randomized controlled trial examining warfarin treatment for IPF was terminated early due to increased death rates. This has led some speculate that specifically may be harmful ILD, and use direct oral anticoagulants (...

Global demand for wood fiber has already led to tremendous harvesting of eastern Siberia’s forest resource. And with timber demand far exceeding supply projections for some of Asia’s most rapidly growing economies, Siberia will continue to play an increasing role in the global timber supply situation. There are foreign investment opportunities in Siberia in the processing of paper and packaging...

Transforming growth factor-B (TGF-B) has been shown to induce apoptotic cell death in normal and transformed hepatocytes. We recently identified tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as an important mediator of TGF-B–induced apoptosis in hepatoma cells. In this study, we have further explored the mechanism by which TGF-B up-regulates TRAIL expression. The 5¶-flanking r...

I first summarize Baltag and Smets’ contribution to this volume, and praise their work. Then I compare the anti-lexicographic plausibility update that they propose to a proposal by Aucher, as an illustration of the difference between a qualitative and a quantitive formulation of updates. I quote Spohn’s original work that is at the root of research in plausibility updates and of the notion of a...